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Coats' Plus: A Progressive Familial Syndrome of Bilateral Coats' Disease, Characteristic Cerebral Calcification, Leukoencephalopathy, Slow Pre- and Post-Natal Linear Growth, and Defects of Bone Marrow and Integument

research Coats' Plus: A Progressive Familial Syndrome of Bilateral Coats' Disease, Characteristic Cerebral Calcification, Leukoencephalopathy, Slow Pre- and Post-Natal Linear Growth and Defects of Bone Marrow and Integument

80 citations , March 2004 in “Neuropediatrics”

Coats' Plus is a genetic disorder with eye abnormalities, brain calcification, poor growth, bone and skin issues, and movement disorders.

research Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin

82 citations , March 2012 in “Development”

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Smad1 and Smad5 but Not Smad8 Establish Stem Cell Quiescence Critical for Transforming Premature Hair Follicles During Morphogenesis to the Postnatal State

research Smad1 and 5 but Not Smad8 Establish Stem Cell Quiescence Which Is Critical to Transform the Premature Hair Follicle During Morphogenesis Toward the Postnatal State

31 citations , September 2013 in “Stem Cells”

Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.

research Akt2 and SGK3 are both determinants of postnatal hair follicle development

24 citations , May 2009 in “The FASEB Journal”

Akt2 and SGK3 are both important for normal hair growth and development.

Targeted Expression of Human Vitamin D Receptor in the Skin Promotes the Initiation of the Postnatal Hair Follicle Cycle and Rescues Alopecia in Vitamin D Receptor Null Mice

research Targeted Expression of Human Vitamin D Receptor in the Skin Promotes the Initiation of the Postnatal Hair Follicle Cycle and Rescues the Alopecia in Vitamin D Receptor Null Mice

57 citations , April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology”

Vitamin D receptor is crucial for starting hair growth after birth.

research Mesenchymal–epithelial interactions during hair follicle morphogenesis and cycling

300 citations , August 2012 in “Seminars in Cell & Developmental Biology”

The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.

research Molecular evolution of HR, a gene that regulates the postnatal cycle of the hair follicle

9 citations , July 2011 in “Scientific Reports”

Changes in the HR gene have influenced hair growth and may lead to hair loss conditions in humans.

Significant Correction of Disease After Postnatal Administration of Recombinant Ectodysplasin A in Canine X-Linked Ectodermal Dysplasia

research Significant Correction of Disease after Postnatal Administration of Recombinant Ectodysplasin A in Canine X-Linked Ectodermal Dysplasia

109 citations , October 2007 in “American Journal of Human Genetics”

Giving a special protein to dogs with a certain genetic disease improved their symptoms but didn't help with hair growth.

research The Vitamin D Receptor Is Required for Mouse Hair Cycle Progression but not for Maintenance of the Epidermal Stem Cell Compartment

25 citations , March 2008 in “The journal of investigative dermatology/Journal of investigative dermatology”

Vitamin D Receptor is needed for hair growth in mice but not for skin stem cell maintenance.

research Molecular Genetic and Endocrine Mechanisms of Hair Growth

51 citations , January 2003 in “Hormone Research in Paediatrics”

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

research Delayed Puberty

15 citations , May 2010 in “Pediatrics in Review”

Delayed puberty often runs in families, can affect growth, and may need hormone treatment.

research Signal transducer and activator of transcription 5B deficiency due to a novel missense mutation in the coiled-coil domain

14 citations , September 2018 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology”

A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.

research 1336 The de novo DNA methyltransferase DNMT3A is required for epidermal homeostasis

April 2018 in “Journal of Investigative Dermatology”

DNMT3A is crucial for healthy skin and hair growth.

research Bone Morphogenetic Proteins and Their Antagonists in Skin and Hair Follicle Biology

176 citations , January 2003 in “Journal of Investigative Dermatology”

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Dermal β-Catenin Activity in Response to Epidermal Wnt Ligands Is Required for Fibroblast Proliferation and Hair Follicle Initiation

research Dermal β-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation

207 citations , March 2012 in “Development”

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

research Cutaneous consequences of inhibiting EGF receptor signaling in vivo: Normal hair follicle development, but retarded hair cycle induction and inhibition of adipocyte growth in EgfrWa5 mice

32 citations , January 2010 in “Journal of Dermatological Science”

Reduced EGFR signaling delays hair cycle and reduces fat growth, but hair development remains normal.

research Regulation of Hair Shedding by the Type 3 IP3 Receptor

19 citations , May 2012 in “The journal of investigative dermatology/Journal of investigative dermatology”

The type 3 IP3 receptor is important for controlling hair loss and growth.

research A human prenatal skin cell atlas reveals immune cell regulation of skin morphogenesis

October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Immune cells are essential for early hair and skin development and healing.

research Hairless: A nuclear receptor corepressor essential for skin function

January 2006 in “Advances in developmental biology”

The Hairless gene is crucial for healthy skin and hair growth.

research De Novo Production of Dermal Papilla Cells during the Anagen Phase of the Hair Cycle

41 citations , June 2010 in “Journal of Investigative Dermatology”

New cells are added to the hair's dermal papilla during the active growth phase.

research 14. Wound Healing; Cutaneous Therapy; Hair

April 2008 in “Medical & surgical dermatology”

Certain hairstyles can cause scalp diseases, smoking is linked to hair loss, 5% minoxidil foam is effective for hair loss treatment, and various factors influence wound healing and hair growth.

research Secretory phospholipase A2-IIA overexpressing mice exhibit cyclic alopecia mediated through aberrant hair shaft differentiation and impaired wound healing response

7 citations , September 2017 in “Scientific Reports”

Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.