119 citations
,
May 1987 in “The Journal of Dermatologic Surgery and Oncology” Most patients' skin darkening after sclerotherapy fades on its own within 6-24 months.
2 citations
,
January 2002 Melanin and melanocytes contribute to the brown pigmentation in stasis dermatitis.
31 citations
,
February 1999 in “Dermatologic surgery” Sun exposure after laser hair removal can cause skin darkening, which is hard to treat and requires avoiding UV light.
114 citations
,
April 2004 in “International Journal of Dermatology” Postinflammatory hyperpigmentation causes dark skin patches and needs personalized treatment.
October 2019 in “International journal of research in dermatology” Misusing topical corticosteroids can cause skin darkening and other side effects.
August 2025 in “Journal of Cosmetic Dermatology” Topical treatments and lasers can improve axillary hyperpigmentation, but no best method is established yet.
12 citations
,
January 2021 in “Dermatology Research and Practice” The 1927 nm Thulium laser effectively and safely treats postinflammatory hyperpigmentation in darker skin tones.
1 citations
,
April 2015 in “Neurology” Skin pigmentation increases in CRPS-affected areas and improves with symptom relief.
November 2025 in “International Journal of Advanced Research” Platelet-rich plasma therapy effectively treated laser-induced skin lightening.
8 citations
,
December 2006 in “Journal of Vascular Surgery” Foam sclerotherapy for varicose veins may cause unexpected hair growth.
July 1996 in “Hair transplant forum international” Using tretinoin and hydroquinone can speed up the fading of skin pigmentation.
November 2023 in “Journal of the American Academy of Dermatology” Skin of color can spontaneously repigment after a phenol-croton oil chemical peel.
2 citations
,
September 2023 in “PubMed” Laser-assisted prostaglandin analogs improve hypopigmented scars safely, but more research is needed.
15 citations
,
March 2015 in “Experimental Dermatology” Clotrimazole, an antifungal cream, may safely reduce skin pigmentation by breaking down the enzyme needed for making melanin.
1 citations
,
July 2015 in “British Journal of Dermatology” Imiquimod improved skin pigmentation in most patients with xeroderma pigmentosum and may prevent further skin cancer, but some treatments can have side effects.
18 citations
,
April 1989 in “Clinics in Dermatology” The argon gas-based cryotherapy effectively reduced keloid scars but caused some hypopigmentation and had a recurrence rate, especially in Afro-American patients.
2 citations
,
January 2023 in “Dermatologic Therapy” CEFFE injections effectively and safely improve postinflammatory hyperpigmentation.
8 citations
,
December 1997 in “International Journal of Dermatology” The patient has a leg condition caused by vein issues, needing lifestyle changes and leg care.
4 citations
,
September 2017 in “Dermatologic surgery” The combination therapy improved skin pigmentation.
2 citations
,
May 2018 in “Dermatologic Surgery” 36 citations
,
June 2016 in “Journal of dermatological treatment” The combination therapy significantly improved Riehl’s melanosis in patients without serious side effects.
38 citations
,
May 1982 in “PubMed” Intralesional steroid injections can effectively treat calcinosis and ulcers in scleroderma.
April 2003 in “Journal of Cutaneous Medicine and Surgery” Lasers are effective for some skin conditions but can cause side effects like scarring and pigment changes; careful selection is important, and botulinum toxin type A is successful in reducing sweat in palmar hyperhidrosis.
56 citations
,
December 1978 in “The Journal of Dermatologic Surgery and Oncology” Transplanting small skin grafts can successfully repigment leukoderma.
5 citations
,
November 2013 in “Case reports in dermatology” A woman's skin darkened after using dutasteride and pimecrolimus for hair loss, but improved when she stopped the medications and protected her skin from light.
1 citations
,
August 2018 in “Dermatologic Surgery”
1 citations
,
January 2001 in “Dermatologic Surgery” Pulsed dye laser and hydrogel dressings effectively treat hypertrophic scars.
14 citations
,
January 2012 in “International Journal of Dermatology” A woman got a rare condition called oleoma after cellulite treatment, which left scars even after treatment.
37 citations
,
October 2017 in “Advanced drug delivery reviews” The review suggests that there are various treatments to help restore skin color after severe burns.
March 2025 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” Facial hyperpigmentation improved with oral isotretinoin and ivermectin cream after Demodex mites were identified as the cause.