July 2011 in “Springer eBooks” The document concluded that FDA-approved treatments like minoxidil and finasteride are effective for hair loss, while the effectiveness of natural remedies and other non-approved treatments is not well-supported by evidence.
Caffeine can potentially treat common hair loss by counteracting hair follicle shrinkage caused by hormones.
October 2020 in “Journal of Pakistan Association of Dermatology” Platelet-rich plasma therapy is more effective than minoxidil lotion for increasing hair count in men with hair loss, with mild side effects and high satisfaction.
November 2019 in “Actas Dermo-Sifiliográficas” Oral minoxidil helps treat hair loss and has reversible side effects.
18 citations
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January 2013 in “International Society of Hair Restoration Surgery” Proper cell preservation is crucial for successful hair transplants and other medical treatments.
1 citations
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March 2020 in “Journal of Pharmacological Sciences” Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.
The model explains how mammal ear hair cells respond to sound and adapt.
July 2018 in “Kidney international” Genetic testing for EGFR mutations is crucial in similar cases.
229 citations
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August 2002 in “Experimental Gerontology” AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.
91 citations
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April 2011 in “Journal of Ethnopharmacology” Polygonum multiflorum extract helps grow hair by activating certain hair growth signals in mice.
70 citations
,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
65 citations
,
July 2020 in “Science Advances” Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.
63 citations
,
April 2003 in “Journal of The European Academy of Dermatology and Venereology” Minoxidil use increases facial hair growth in females, more in older users.
59 citations
,
May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
46 citations
,
August 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” Phosphatidic acid may help hair grow by affecting cell growth pathways.
33 citations
,
January 2002 Latanoprost, a glaucoma drug, showed potential for promoting hair growth in bald monkeys, especially at higher doses.
32 citations
,
December 2013 in “Biological & Pharmaceutical Bulletin” Rice bran extract can potentially treat hair loss by promoting hair growth and increasing the number of hair follicles.
27 citations
,
September 2017 in “Journal of Medicinal Food” Annurca apple supplement safely increases hair growth and keratin in humans.
27 citations
,
September 2017 in “Archives of Dermatological Research” Topical tofacitinib may grow hair better than minoxidil by increasing VEGF and reducing inflammation.
25 citations
,
June 2011 in “International journal of pharmaceutics” Nanoparticles effectively deliver water-insoluble drugs to hair follicles, stimulating hair growth without irritating the skin.
24 citations
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October 2016 in “Oncotarget” Finasteride has a higher risk of reproductive side effects than minoxidil.
23 citations
,
May 1998 in “Journal of Dermatological Science” Insulin or IGF-I is needed for hair growth in newborn mice, while minoxidil helps adult mouse hair grow, suggesting a way to study human hair loss.
21 citations
,
January 2015 in “Journal of Dermatological Science” Ginsenosides in Panax ginseng boost hair growth like minoxidil.
19 citations
,
June 2020 in “International Journal of Dermatology” Low-dose oral minoxidil effectively treats non-scarring hair loss with some side effects like hypertrichosis and postural hypotension.
19 citations
,
October 2009 in “Bioorganic & Medicinal Chemistry Letters” Thyroid receptor agonists may treat male pattern baldness without harmful side effects.
19 citations
,
August 2000 in “International Journal of Dermatology” Minoxidil and finasteride can slow or halt hair loss, but may have side effects.
16 citations
,
October 2019 in “Biological & Pharmaceutical Bulletin” Houttuynia cordata extract may help hair grow by improving cell survival and increasing cell growth.
16 citations
,
August 2004 in “Tetrahedron” Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.
15 citations
,
April 2001 in “Journal of Dermatological Science” KF19418 promotes hair growth similarly to minoxidil but is not better in live mice.
13 citations
,
December 2017 in “BMC Complementary and Alternative Medicine” The Asian herbal mix with Houttuynia cordata, Perilla frutescens, and green tea helped grow hair in mice.