54 citations
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July 2017 in “Scientific Reports” JMJD3 and NF-κB activate Notch1, which is essential for skin cell movement and wound healing.
43 citations
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August 2010 in “Expert Opinion on Investigational Drugs” Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
31 citations
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February 2021 in “Nutrients” Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.
31 citations
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May 2019 in “Nature communications” Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.
27 citations
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February 2020 in “Journal of Cardiovascular Translational Research” Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.
25 citations
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March 2018 in “Clinics in Dermatology” Indigenous herbal medicines in the Indian subcontinent have potential for drug development but need more research and standardization.
24 citations
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December 2018 in “Life sciences” Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
24 citations
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December 2009 in “Future Medicinal Chemistry” Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
23 citations
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April 2021 in “Journal of Clinical Medicine” Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.
22 citations
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June 2012 in “PLOS ONE” Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.
21 citations
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March 2018 in “Experimental Dermatology” The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
20 citations
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October 2008 in “European journal of endocrinology” Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.
18 citations
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July 2021 in “Molecular Medicine Reports” The WNT signaling pathway is crucial for mesenchymal stem cells' function and therapy success.
18 citations
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September 2020 in “International Journal of Nanomedicine” Both human and animal-derived small extracellular vesicles speed up skin healing equally well.
14 citations
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December 2010 in “Dermatologica Sinica” New treatments for hair loss show promise, but more development is needed, especially for tough cases.
3 citations
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June 2022 in “Dermatology and therapy” A new botanical treatment improved hair growth and symptoms in lichen planopilaris patients.
2 citations
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September 2023 in “Curēus” Topical spironolactone may help treat ocular graft-versus-host disease with minimal side effects.
September 2025 in “Journal of Phytonanotechnology and Pharmaceutical Sciences” Licorice has health benefits but can also cause side effects, so it should be used carefully.
September 2023 in “Frontiers in medicine” The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
July 2018 in “Elsevier eBooks” Frontal Fibrosing Alopecia is a type of hair loss affecting mostly older women, with no agreed best treatment.
The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
August 2016 in “Journal of Dermatology” A chemical called 5-Bromo-2′-deoxyuridine caused rapid hair loss in mice by killing certain skin cells through a specific cell death pathway.
252 citations
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April 2009 in “Seminars in Cell & Developmental Biology” The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.
97 citations
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September 2016 in “Reviews in Endocrine and Metabolic Disorders” The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
47 citations
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October 2014 in “Expert Opinion on Emerging Drugs” New alopecia treatments aim for better results and fewer side effects.
34 citations
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October 2024 in “Clinical Cosmetic and Investigational Dermatology” Azelaic acid is effective for treating rosacea, acne, and melasma.
24 citations
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January 2020 in “International Journal of Molecular Sciences” Some plants with flavonoids may help treat hair loss and promote hair growth.
16 citations
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June 2019 in “International Journal of Women's Dermatology” Type 2 diabetes may increase the risk of severe hair loss in African American women.
12 citations
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January 2010 in “Pediatric Health” Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.
9 citations
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April 2019 in “Molecules” Blackcurrant extract may help reduce hair loss by promoting stem cell activity in hair follicles.