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A 21-year-old male with a rare genetic disorder experienced sudden hair loss and high DHEAS levels, likely due to a condition similar to PCOS, usually seen in women.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Seven new genetic risk areas for prostate cancer were found.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

EF and PXE not closely related.

RSPO1 could help create new diabetes treatments by increasing pancreatic β cells.

Increasing PDCD4 protein may help prevent or treat some skin cancers.

Monilethrix is a genetic hair disorder affecting hair shape, seen in two brothers.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Taking 5-alpha reductase inhibitors might be linked to breast cancer in men.

UTX is crucial for skin differentiation and health, especially in females.

Increased ODC expression makes normally tumor-resistant mice more prone to tumor development.

The rs1128977 gene variant may affect cholesterol and body measurements.

CXXC5 can both suppress and promote cancer, making it a complex target for treatment.

The mouse model showed defects in adult stem cell maintenance related to Hutchinson-Gilford progeria syndrome.

CRISPR gene editing reduces harmful molecules in cells from Emery–Dreifuss Muscular Dystrophy patients.

5α-Reductase helps regulate hormone action in toad testes, especially during breeding season.

RAR-gamma 1 is important for normal skin maintenance and differentiation.

The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.

Overexpressing PKCα in mice skin increases inflammation but doesn't affect tumor growth.

Certain genetic variations in the RAB5B gene are linked to a higher risk of polycystic ovary syndrome in Chinese Han women.

PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.

Puerariae Radix extract may be a promising cosmetic ingredient for skin health.

Reduced TRPS1 leads to increased STAT3 and SOX9 in hair follicles, affecting hair growth.

Hair dye ingredient PPD can cause severe allergic reactions, including facial swelling.

PPARγ is crucial for skin health but can have both beneficial and harmful effects.

A 4kb fragment of the desmocollin 3 promoter targets gene expression to specific skin and hair follicle areas.

A new genetic mutation in the TRPS1 gene causes Trichorhinophalangeal Syndrome, leading to specific hair, dental, and bone issues.