research Gender aspects in skin diseases
Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.
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research Chrousos syndrome: from molecular pathogenesis to therapeutic management
The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.
research Idiopathic Hirsutism*
The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.
research Hunting the genes in male‐pattern alopecia: how important are they, how close are we and what will they tell us?
Genes play a significant role in male-pattern baldness, and understanding them could lead to new treatments and insights into related health issues.
research Endocrine-skin interactions
Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.
research Iron Plays a Certain Role in Patterned Hair Loss
Iron deficiency may contribute to hair loss.
research Aging in hair follicle stem cells and niche microenvironment
Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
research Age-related hair changes in men: Mechanisms and management of alopecia and graying
Men's hair loss is caused by hormones and genes, and can be treated with medication and surgery, while graying is due to aging and has no prevention except dyeing.
research Mesotherapy: What is new?
Mesotherapy shows promise for cellulite and facial rejuvenation but has mixed results for body sculpting and hair loss, with more research needed for safety and effectiveness.
research Human Hair Follicle Stem/Progenitor Cells Express Hypoxia Markers
Human hair follicle stem cells show signs of low oxygen levels, which may be important for hair growth and preventing baldness.
research Pharmacologic Modulation of Sebaceous Gland Activity: Mechanisms and Clinical Applications
The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.
research Characteristics of flutamide action on prostatic and testicular functions in the rat
Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.
research The Basic Science of Hair Biology
Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
research Gene expression of type 2 17β hydroxysteroid dehydrogenase in scalp hairs of hirsute women
Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
research Fabrication of a 3D hair follicle‐like hydrogel by soft lithography
Researchers created a 3D hydrogel that mimics human hair follicles, which may help with hair loss treatments.
research Synaptic Long-Term Potentiation and Depression in the Rat Medial Vestibular Nuclei Depend on Neural Activation of Estrogenic and Androgenic Signals
Estrogen and androgen signals control synaptic changes in rat brains.
research Pre-clinical non-viral vectors exploited forin vivoCRISPR/Cas9 gene editing: an overview
Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.
research Alopecia and platelet-derived therapies
Platelet lysate is more effective than activated autologous platelet-rich plasma or saline in improving hair growth after hair restoration surgery.
research Rooster feathering, androgenic alopecia, and hormone-dependent tumor growth: What is in common?
Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.
research The Metabolism and Control Mechanism of Human Hair Follicles
Human hair follicles have a unique metabolism that changes between growth stages and may contribute to baldness.
research Hair Loss and Hirsutism in the Elderly
Many elderly women experience unwanted facial hair and various hair loss conditions, with treatments available for each condition.
research Testosterone Metabolism in Human Skin Cells in vitro and Its Interaction with Estradiol and Dutasteride
Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.
research The endocrinology of baldness
Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.
research Polycystic ovary syndrome and the differential diagnosis of hyperandrogenism
The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.
research A Perspective on the Evolving Landscape in Male Reproductive Medicine
Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.
research New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today’s Pre-Clinical Data into Tomorrow’s Daily Clinical Practice
New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
research Recent updates on Wnt signaling modulators: a patent review (2014-2020)
New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.
research Trends in the Development of New Drugs for Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.
research Early embryonic exposure of freshwater gastropods to pharmaceutical 5-alpha-reductase inhibitors results in a surprising open-coiled “banana-shaped” shell
Certain drugs change freshwater snail shells to a "banana" shape.
research Current Concepts and Translational Uses of Platelet Rich Plasma Biotechnology
Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.