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Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.

Dutasteride use can lead to a stable decline in sexual function that is not affected by age or prostate size.

Carbamazepine may cause reversible nail detachment.

Serenoa repens may cause long-lasting sexual and psychiatric side effects.

The steroids allopregnanolone and allotetrahydrodeoxycorticosteron worsened absence seizures in rats.

Setipiprant may reduce inflammation by blocking an enzyme called aldose reductase.

5alpha-reductase 2 is crucial for proper male brain development and sexual differentiation.

Rat whisker cells can help turn other cells into nerve cells and might be used to treat brain injuries or diseases.

Dupilumab effectively controls symptoms in infants with Netherton syndrome.

The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.

Early-life neurosteroid changes affect adolescent exploration and adult behavior.

Pterostilbene significantly reduces prostate enlargement and has strong antioxidant effects.

Phytochemicals may offer safer alternatives to synthetic drugs for prostate cancer treatment.

Certain natural compounds called terpenes may help prevent prostate cancer.

Doctors should consider Netherton syndrome in patients with chronic skin and hair issues to avoid misdiagnosis.

The conclusion is that maintaining blinding in clinical trials is crucial for reliable results.

A man's severe skin reaction from cancer treatment improved with early diagnosis and proper medication.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

COPD flare-ups worsen life quality and increase hospital visits and costs.

The consensus provides guidelines for safely stopping danazol in hereditary angioedema treatment.

Adolescent sexual development should focus on positive aspects, including biological, psychological, and contextual factors, and recognize individual differences and the role of pleasure.

Shaving and avoiding brushing improved the patient's beard hair condition.

Niosomes improve aminexil's effectiveness in preventing hair loss without needing propylene glycol.

Dexamethasone effectively normalizes elevated steroid levels in girls with premature adrenarche.

Prostate cancer was a major health issue in 2009, especially for Black men, and targeting the 5alpha-reductase enzyme could help in its prevention and treatment.

Some herbs show promise as antiandrogenic agents.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.