research Spectrum and signals of medication-associated cognitive disorder: a comprehensive disproportionality analysis with cross-database validation
Many medications may be linked to cognitive disorders, but most lack warnings on labels.
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630-660 / 1000+ resultsresearch The temptation of large numbers
Large databases in research can lead to misleading conclusions due to biases and chance findings; researchers should analyze data more rigorously.
research A Gender Hypothesis of sex disparities in adverse drug events
Gendered social factors, not just biology, contribute to sex differences in adverse drug events.
research One of These Things Is Not Like the Others: The Idea of Precedence in Health Technology Assessment and Coverage Decisions
The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.
research Patient, Oncologist, and Payer Preferences for Adjuvant Endocrine Therapy and CDK4/6 Inhibitor Regimens in Early-Stage Breast Cancer: A Discrete Choice Experiment
Patients and oncologists prioritize survival benefits, while payers focus on treatment costs.
research Closing the AI generalization gap by adjusting for dermatology condition distribution differences across clinical settings
Adjusting AI training data for skin condition distribution improves accuracy across different clinical settings.
research Former finasteride users with sexual side effects at increased risk for depressive symptoms, suicidal thoughts
Men with sexual side effects from finasteride may face higher risks of depression and suicidal thoughts.
research Bias in Hair Cortisol Measures for Psychological Stress: Self vs. Professional Collection
Self-collected hair samples can measure stress but may need adjustments for accuracy.
research Peer Review #3 of "Computational drug repositioning based on side-effects mined from social media (v0.1)"
Reviewers criticized the study for assuming drugs with similar side-effects work the same way and questioned the validity of its findings due to potential biases and data quality issues.
research The nocebo effect: A clinicians guide
Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.
research Consultant appraisal: pitfalls and how to avoid them
Learn how to avoid mistakes in consultant evaluations.
research 1450 THE TRUE BENEFIT OF PSA-SCREENING: MODELING THE IMPACT OF TRIAL SETTING AND PROTOCOL ON MORTALITY
PSA screening's effectiveness in reducing prostate cancer deaths can vary based on trial design and participant compliance.
research Factors that Affect Brand Loyalty and Customer Advocacy: the Moderating Role of Greenwashing
Green perceived value and altruistic value boost brand loyalty and advocacy, but greenwashing perception can change this effect.
research Evidence Synthesis Gone Awry: The Perils of Aggregating Ineffective or Unsafe Doses in Alopecia Areata Reviews
Including ineffective or unsafe doses in reviews can lead to misleading conclusions about alopecia areata treatments.
research Review of: "“Toupee or not Toupee?” Sic (et Non). Social perceptions of Male Pattern Baldness (Androgenetic Alopecia)"
The review suggests the study on male pattern baldness needs more detail on sample size, methodology, bias, and ethical considerations.
research Finasteride toxicity information: “limited”, “poor quality”, “biased”
Finasteride toxicity information is limited, poor quality, and biased.
research Social Interest Data as a Proxy for Off-Label Performance-Enhancing Drug Use: Implications and Clinical Considerations
Clinicians should use social and prescription data to track trends in performance-enhancing drug use.
research Screening: seeking a balance
The document concludes that better training and education are needed for proper cancer screening and criticizes the GMC's inaction as harmful to clinical ethics in the UK.
research Controversies: Is Finasteride Safety Data Adequately Reported in Published Trials?
Finasteride safety data in trials may be underreported or misrepresented.
research The commoditization of surgical hair restoration—a cautionary statement
Prioritizing cost over expertise in hair restoration can lower care quality.
research Addressing continuous data for participants excluded from trial analysis: a guide for systematic reviewers
The conclusion is that the risk of losing significance in meta-analysis results increases with smaller effects and more missing data, and using the median standard deviation for imputation is recommended.
research LB1011 Cost and access changes with TNFa inhibitor biosimilars entering the market
Biosimilars lower costs but don't significantly improve access.
research P.6.028 Transnosography of impulsiveness:A comparison among different psychiatric disorders
Impulsiveness is common across various psychiatric disorders and linked to many psychological symptoms.
research AGA practitioner challenges: A mixed‐methods pilot survey
Practitioners treating hair loss need better education and resources to overcome challenges like commercial bias and ethical dilemmas.
research A Radiation Oncologist Writes
Patient care should come before profit in medicine.
research Index of the human papillomavirus (HPV) vaccine industry clinical study programmes and non-industry funded studies: a necessary basis to address reporting bias in a systematic review
All HPV vaccine studies should be registered and published to reduce reporting bias.
research A response to “Inconsistent platelet-rich plasma product from the Food and Drug Administration cleared devices: A retrospective review of clinic data”
Inconsistent platelet counts in PRP are due to varying blood volumes, preparation methods, and analyzer types.
research Evaluating the safety profile of α-1 blockers, 5α-reductase inhibitors, and PDE5I for BPH: a disproportionality analysis of real-world adverse events based on FDA adverse event reporting system (FAERS)
PDE5 inhibitors cause earlier adverse events in BPH treatment, requiring careful monitoring.
research Aspect-Level Drug Reviews Sentiment Analysis Based on Double BiGRU and Knowledge Transfer
A model called PM-DBiGRU was developed for analyzing sentiments in drug reviews, and it performed better than other models, but struggled with complex sentences and situations requiring background knowledge.
research Explaining and predicting the single channel versus multi-channel consumer: the case of an embarrassing product
The Theory of Planned Behaviour predicts consumer behavior better when emotions, personality, demographics, and marketing are included.