April 2017 in “Journal of Investigative Dermatology” PRC1 influences skin stem cell development by both turning genes on and off, affecting hair growth and skin cell types.
12 citations
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April 2022 in “Journal of Bioscience and Bioengineering” Activating the PI3K/Akt pathway improves hair growth by human dermal papilla cells in hair beads.
January 2023 in “Journal of Cosmetic Dermatology” PRP is effective for treating hair loss, improving hair density, count, and thickness.
12 citations
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June 2018 in “Journal of Cosmetic Dermatology” PRP is effective for hair loss and might work better with other treatments, but more research is needed.
6 citations
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August 2022 in “Dermatologic therapy” PRP therapy can temporarily grow hair in CCCA patients but isn't a permanent cure.
May 2026 in “Ibero-American Journal of Health Science Research” Regenerative therapies, including platelet-rich plasma (PRP) and stem cells, are revolutionizing dermatology and aesthetic medicine by offering innovative solutions for tissue rejuvenation and repair. PRP, derived from the patient's blood, is rich in growth factors that stimulate cell proliferation and collagen synthesis, promoting effective tissue regeneration. Stem cells, mainly from bone marrow or adipose tissue, can differentiate into various cell types and actively participate in reparative processes. This narrative review highlights the biological foundations, clinical applications, and recent advances of these therapies, emphasizing their safety, efficacy, and transformative potential in aesthetics. It also discusses current limitations and future prospects, stressing the need for more robust clinical studies to standardize protocols and optimize outcomes, ultimately representing a promising approach to personalized, minimally invasive treatments in regenerative dermatology.
Combining PRP with minoxidil improves hair growth more than minoxidil alone.
Combining ATRA with TPO-RA effectively stabilizes platelet counts in ITP patients.
505 citations
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October 2011 in “Journal of clinical oncology” MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
20 citations
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December 2021 in “Journal of the American Academy of Dermatology” Continuous treatment with ritlecitinib and brepocitinib is needed to maintain hair regrowth in alopecia areata.