January 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Collagen supplements may improve skin and joint health but have inconsistent effects on blood sugar and heart health.
24 citations
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September 2024 in “Journal of Investigative Dermatology” January 1993 in “Di-Si Junyi Daxue xuebao” Type III collagen increases in recovering guinea pig skin, aiding tissue stability.
10 citations
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January 2024 in “Dermatology Research and Practice” A 12-week randomized, double-blind, placebo-controlled study evaluated the effects of a supplement containing hydrolysed collagen and vitamin C on skin, scalp, and hair. The study found that the supplement, taken daily or every 48 hours, improved dermal collagen, hydration, elasticity, and reduced wrinkles, as well as enhanced scalp and hair condition. These results were measured using confocal microscopy, high-resolution ultrasound, and clinical trichoscopy, with significant improvements observed by week 12. The study supports the clinical benefits of the supplement for combating signs of aging.
May 2024 in “Animal genetics” A cat's poor wound healing was linked to a genetic deletion in the COL5A1 gene.
14 citations
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February 2011 in “Experimental dermatology” A protein called COMP is part of the connective tissue in normal human hair follicles and may be important for hair health.
42 citations
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February 2000 in “Journal of Investigative Dermatology” Type VII collagen absence helps skin development by allowing tissue remodeling.
18 citations
,
February 2015 in “Acta Crystallographica Section D: Structural Biology” The study concludes that certain domains in Clostridium histolyticum enzymes are structurally unique, bind calcium to become more stable, and play distinct roles in breaking down collagen, with potential applications in medicine and drug delivery.
34 citations
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September 2020 in “Clinical, cosmetic and investigational dermatology” Hyaluronic acid increases collagen synthesis safely, while poly-L-lactic acid may cause complications by affecting fibroblasts.
22 citations
,
May 2004 in “Tissue Engineering” PGA fiber-reinforced collagen sponges improve hair growth and skin structure.
July 2025 in “Journal of Investigative Dermatology” Collagen scaffolds in cell therapy can transform skin to be more resilient and pressure-responsive.
April 2024 in “UNESP Institutional Repository (São Paulo State University)” Alpaca skin has glands, hair follicles, and different collagen types.
June 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” The RHC complex with nicotinamide promotes hair growth and health.
June 2023 in “Research Square (Research Square)” Hyaluronic acid and polycaprolactone improve skin regeneration, with polycaprolactone having a stronger effect on healing and tissue repair.
January 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Collagen supplements may modestly improve skin and joint health, but effects on metabolism and blood sugar are inconsistent.
Collagen VI is crucial for nerve function and affects wound-induced hair regrowth.
September 2024 in “Journal of the American Academy of Dermatology” PRO-C22 can help diagnose and monitor the severity of hidradenitis suppurativa.
October 2013 in “Journal of Investigative Dermatology” Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.
26 citations
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January 2015 in “PubMed” Collagenase IV helps control hair growth by affecting certain growth factors.
3 citations
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May 1991 in “Journal of Investigative Dermatology” 3 citations
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January 2014 Collagen XVIII and Bmx tyrosine kinase are important for hair growth and skin cancer development.
18 citations
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January 2000 in “Journal of Adhesion Science and Technology” Modified artificial hair with collagen improves tissue adhesion and is safe for long-term use.
11 citations
,
August 1995 in “Journal of Investigative Dermatology” 1 citations
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June 2018 in “Ukrainian Journal of Dermatology Venerology Cosmetology” Oral collagen improves skin, nails, hair, and reduces cellulite.
November 2023 in “International Journal of Pharmaceutics” New hair loss treatment using marine collagen and dissolvable needles improves hair growth.
December 2025 in “PubMed” Fish collagen peptide may boost hair growth and health.
September 2018 in “Chinese Journal of Dermatology” Angiogenin may help treat hair loss by reducing certain proteins in hair cells.
11 citations
,
April 2020 in “Nutrafoods - International Journal on Nutraceuticals, Functional Foods and Novel Foods” Taking Bioactive Collagen Peptides increases hair thickness.
7 citations
,
December 1991 in “Annals of the New York Academy of Sciences” Dermal papillae are crucial for hair growth and maintenance.
1 citations
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January 2005 in “Experimental Dermatology” MC-1R in skin cells may influence inflammation and collagen production.