1 citations
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December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Sox9 levels in brain stem cells affect whether they stay as stem cells or become neurons.
143 citations
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September 2008 in “Experimental gerontology” Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
44 citations
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September 2016 in “American Journal Of Pathology” Neural crest-derived progenitor cells in the cornea could help treat corneal issues without transplants.
2 citations
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October 2023 in “Philosophical Transactions of the Royal Society B Biological Sciences” Different PADI isoforms help cells develop diverse functions.
Ca²⁺-mediated protein citrullination controls cell growth in the CNS and may help treat brain tumors.
January 2020 in “Research Portal Denmark” A short male anogenital distance may indicate incomplete masculinization due to disrupted androgen action.
Activin A promotes ear hair cell development, while follistatin delays it.
212 citations
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January 2017 in “Mediators of Inflammation” Stem cells show promise in speeding up wound healing and tissue regeneration.
35 citations
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November 2020 in “Experimental Dermatology” Different types of skin cells are organized in a special way in large wounds to help with healing and hair growth.
25 citations
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August 2010 in “Journal of Biological Chemistry” Nuclear Factor I-C is important for controlling hair growth by affecting the TGF-β1 pathway.
19 citations
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January 2013 in “Frontiers in Neuroanatomy” Zebrafish can help study and develop treatments for hearing loss.
12 citations
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August 2016 in “Current opinion in genetics & development” Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.
2 citations
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November 2015 in “Actas Dermo-Sifiliográficas” Epidermal stem cells show promise for future dermatology treatments due to ongoing advancements.
August 2019 in “Journal of Invertebrate Pathology” Thymosin beta 4 protects cells from damage by blocking a harmful microRNA and boosting a protective gene.
88 citations
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July 2019 in “International Journal of Molecular Sciences” Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.
41 citations
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June 2010 in “Journal of Investigative Dermatology” New cells are added to the hair's dermal papilla during the active growth phase.
31 citations
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January 2014 in “International Journal of Trichology” The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.
22 citations
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June 2013 in “International journal of molecular sciences” Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
4 citations
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January 2013 in “Humana Press eBooks” Scientists found ways to identify and collect skin stem cells, which vary by skin area and are delicate.
March 2021 in “Cell stem cell” Skin cell behavior is influenced by the tightness of nearby cells, affecting their growth and development.
211 citations
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May 2018 in “Trends in cell biology” Different types of skin cells play specific roles in development, healing, and cancer.
129 citations
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May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
75 citations
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September 2017 in “Developmental biology” The circadian clock influences the behavior and regeneration of stem cells in the body.
57 citations
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April 2009 in “Differentiation” SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
6 citations
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April 2024 in “Journal of Investigative Dermatology” CRISPR-based tools improve understanding and treatment of skin development and conditions.
4 citations
,
September 2020 in “Stem Cell Research & Therapy” Xenobiotic-free progenitor cells improve wound healing and blood vessel formation.
April 2016 in “Journal of Investigative Dermatology” The symposium showed that stem cells are key for understanding and treating skin diseases and for developing new skin models and therapies.
April 2018 in “Journal of Investigative Dermatology” Hair follicle stem cells can change their role to ensure proper hair development.
19 citations
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April 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
46 citations
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December 1998 in “Journal of Biological Chemistry” Keratin 19 forms less stable and shorter filaments than keratin 14, giving unique traits to certain skin cells.