research Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments
Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
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research Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53
Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.
research Lineage Analysis of Epidermal Stem Cells
Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
research A practical guide for the study of human and murine sebaceous glands in situ
The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.
research JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin
JunB is crucial for maintaining healthy skin and hair follicles.
research Transient mitochondrial DNA double strand breaks in mice cause accelerated aging phenotypes in a ROS-dependent but p53/p21-independent manner
Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.
research GRHL3 binding and enhancers rearrange as epidermal keratinocytes transition between functional states
GRHL3 is important for controlling gene activity in skin cells during different stages of their development.
research Destruction of the arrector pili muscle and fat infiltration in androgenic alopecia
Hair loss in male pattern baldness involves muscle degeneration and increased scalp fat.
research Beyond goosebumps: Does the arrector pili muscle have a role in hair loss?
The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.
research Dormancy in the stem cell niche
Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.
research Stem Cells behind the Barrier
Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
research Intravital imaging of hair-cell development and regeneration in the zebrafish
Zebrafish can help study and develop treatments for hearing loss.
research Follistatin promotes LIN28B-mediated supporting cell reprogramming and hair cell regeneration in the murine cochlea
Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.
research Quorum sensing and other collective regenerative behavior in organ populations
Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.
research Biofabrication of Human Skin with Its Appendages
Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
research Rejuvenation: an integrated approach to regenerative medicine
Rejuvenating self-repair mechanisms could improve organ recovery in regenerative medicine.
research GDNF promotes hair formation and cutaneous wound healing by targeting bulge stem cells
GDNF helps grow hair and heal skin wounds by acting on hair stem cells.
research Exposure to gamma-rays at the telogen phase of the hair cycle inhibits hair follicle regeneration at the anagen phase in mice
Gamma-rays exposure during the resting phase of hair growth can damage hair regeneration and color in mice.
research Genetic Tools for Cell Lineage Tracing and Profiling Developmental Trajectories in the Skin
CRISPR-based tools improve understanding and treatment of skin development and conditions.
research Hairless controls hair fate decision via Wnt/β–catenin signaling
The Hairless gene is crucial for hair cell development, affecting whether skin cells become hair or skin and oil gland cells.
research Skin Cyst: A Pathological Dead-End With a New Twist of Morphogenetic Potentials in Organoid Cultures
Skin cysts might help advance stem cell treatments to repair skin.
research Skin Deep and Deeper: Multiple Pathways in Basal Cell Carcinogenesis
The research suggests new treatments for skin cancer could target specific cell growth pathways.
research Isolation and Characterization of Cutaneous Epithelial Stem Cells
Scientists found ways to identify and collect skin stem cells, which vary by skin area and are delicate.
research Skin Stem Cells: At the Frontier Between the Laboratory and Clinical Practice. Part 1: Epidermal Stem Cells
Epidermal stem cells show promise for future dermatology treatments due to ongoing advancements.
research DNA Methylation as an Epigenetic Memory Keeper during Skin Development and Regeneration
DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.
research Stem Cells and their Niches
The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
research Advances In Mesenchymal Cell Therapy In Dermatology And Aesthetic Medicine
Mesenchymal stem cells improve skin appearance and structure in dermatology and aesthetic medicine.
research Aligning Stem Cell Models and Postmortem Studies to Query Striatal Neurodevelopment in Schizophrenia
Schizophrenia risk genes may affect early brain development, contributing to the disease.
research Transcriptomic landscape of early hair follicle and epidermal development
Researchers identified new cell types and genes in early hair follicle development.
research Immunohistochemical Expression of Sox9 and CD34 in Androgenetic Alopecia Patients
CD34+ cells decrease in bald areas, while Sox9 stays high, suggesting hair loss in AGA is linked to stem cell issues.