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Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Modifying steroidal inhibitors shows promise for developing new cancer treatments.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Finasteride is mainly broken down by the enzyme CYP3A4, affecting its levels in the body.

A transman experienced lasting virilization symptoms after stopping testosterone, which were resolved with estradiol treatment.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Some synthesized compounds were more effective than Finasteride in reducing prostate cancer cell growth and androgen levels.

A woman's hair loss and other symptoms were due to a rare hormone deficiency treatable with steroids.

Steroid hormone binding in rat skin varies with pH, heat, and hair cycle phases.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

New steroid derivatives show promise as anticancer agents, even against resistant cells.

Hirsutism is excessive male-pattern hair growth in women, often treated cosmetically or with hormone therapy if contraception is also desired.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Neurosteroids help control dopamine responses in the brain.

Diagnosing simple-virilizing congenital adrenal hyperplasia can be difficult and requires thorough testing and expert advice.

A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.

The mutated hairless gene causes hair loss by acting as a new type of corepressor affecting thyroid hormone receptors.

Adding cerium(III) chloride to Grignard reagents improves the making of compounds that could treat prostate issues and hair loss.

A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.

Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.

Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.

Human skin can produce steroids from cholesterol.

New genotype linked to non-classical congenital adrenal hyperplasia found in Italian siblings.

Estrogen deficiency can reduce the enzyme activity needed to activate vitamin D.

The patient with severe hirsutism improved after being diagnosed with non-classic congenital adrenal hyperplasia and treated with corticosteroids.

Steroid sulfatase inhibitors could help treat hormone-related disorders and cancers.

Androsterone and finasteride have different solid forms, with new findings correcting previous errors and identifying a new form.