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Hormone therapy for trans individuals is effective and generally safe in the short term.

Women also use 5α-reductase inhibitors for hair loss and hirsutism.

Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The compound 4c effectively inhibits the enzyme linked to hair loss.

Blocking certain brain processes reduces mating behavior in female rats.

Estrogens and androgens are crucial for male fertility.

The equine epididymis mainly uses type 1 5α-reductase, and both finasteride and dutasteride can inhibit its activity.

Gender-affirming hormone treatments need better patient-focused outcome measurements and standardized data collection.

High doses of progesterone can reduce seizures in mice.

Plant-based compounds may offer safer prostate cancer treatment with fewer side effects.

Androgens boost certain nest-building behaviors and greatly reduce food intake in rabbits.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.

The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.

Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.

Human adrenals and gonads have a unique enzyme for steroid hormone production.

Male cells need DHT to respond to testosterone, while female cells do not.

Hormones like testosterone and estrogen significantly affect hair growth and structure.

Abusing anabolic steroids can cause serious health problems despite short-term muscle gains.

This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.

Hormone therapy for excessive hair growth is as good with GnRHa as with high-dose CPA, but GnRHa has longer-lasting results.

Monitoring steroid hormones in blood can better detect testosterone doping.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Topical 17 alpha-propylmesterolone increases hair cell growth in androgenetic alopecia.

Differences in enzyme activity and androgen receptors in hair follicles may explain why hair loss appears differently in men and women.

Allopregnanolone, a progesterone metabolite, helps reduce restraint effects on behavior.