research Estimating the Contribution of the Prostate to Blood Dihydrotestosterone
The normal human prostate does not significantly affect blood DHT levels.
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780-810 / 1000+ results research The Metabolism of Dehydroepiandrosterone by Human Scalp Hair Follicles
Altered DHEA metabolism in hair follicles may be linked to hair loss in balding men.
research Antiandrogen Drugs Lower Serum Prostate-Specific Antigen (PSA) Levels in Hirsute Subjects: Evidence That Serum PSA Is a Marker of Androgen Action in Women1
Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.
research Skin permeation of different steroid hormones from polymeric coated liposomal formulations
Polymers increased skin permeation and stability of steroid hormones in liposomal formulations.
research Androgens and ovarian function: translation from basic discovery research to clinical impact
Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
research Abstract SS02-02: Chemoprevention: Poised for Success
Chemoprevention can significantly lower cancer risks and needs more research and collaboration.
research Testosterone: The Male Sex Hormone
More research is needed to understand how testosterone is maintained in adult males.
research Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor
Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.
research Impaired Cardiometabolic Effects of Bromocriptine in Men With Early‐Onset Androgenic Alopecia
Men with early-onset hair loss have less cardiometabolic benefit from bromocriptine.
research Steroid sulfatase inhibitors
Steroid sulfatase inhibitors could help treat hormone-related disorders and cancers.
research Comparison of a gonadotropin-releasing hormone agonist and a low dose oral contraceptive given alone or together in the treatment of hirsutism.
Combining a GnRH agonist with a low-dose oral contraceptive is more effective and safer for treating hirsutism than using either alone.
research 17α‐estradiol induces aromatase activity in intact human anagen hair follicles ex vivo
17α-estradiol boosts aromatase activity in female hair follicles, potentially helping with hair loss.
research Effect of Exogenous Testosterone, Finasteride, and Castration on serum level of Thyroxin
Testosterone changes reduce thyroxin levels in rats.
research Testosterone protects female embryonic heart H9c2 cells against severe metabolic stress by activating estrogen receptors and up-regulating IES SUR2B
Testosterone protects female heart cells from stress by activating estrogen receptors.
research Local stimulation of sebaceous gland activity by the topical administration of dehydroepiandrosterone
Topical DHEA safely increases skin oil production.
research Development of a novel, clinically-relevant model for investigating factors that stimulate human hair growth
Testosterone stimulates growth in intermediate hair follicles, but this can be blocked by cyproterone acetate.
research Epigenetic Effects of Finasteride on Dopaminergic Signaling Pathways: A potential contributor to Post-Finasteride Syndrome
Finasteride may cause changes in dopamine-related genes, possibly leading to post-finasteride syndrome.
research Hormone therapy for transgender patients
Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.
research History as a Tool in Identifying “New” Old Drugs
Finasteride, originally for prostate issues, also treats hair loss, similar to effects from certain plants.
research In vitrometabolism of dehydroepiandrosterone and testosterone by canine hair follicle cells
Canine hair follicle cells metabolize DHEA and testosterone differently than human cells.
research Alterations in androgen conjugate levels in women and men with alopecia
Women with hair loss have higher androgen levels, while men with early balding have altered androgen ratios.
research The challenging role of antiandrogens in the management of polycystic ovary syndrome
Antiandrogens are used to manage polycystic ovary syndrome by reducing androgen levels or controlling their effects, often combined with lifestyle changes and other treatments.
research Progesterone regulates corticosterone elevation and alterations in spatial memory and exploratory behavior induced by stress in Wistar rats
Progesterone helps protect against stress-related memory and behavior issues in rats.
research Modulation of Androgen Receptor Transcriptional Activity
Androgen receptor activity is influenced by hormones, co-factors, modifications, and mutations.
research Urinary steroids in women with androgenic alopecia
Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.
research Effects of testosterone, dihydrotestosterone and estradiol on the growth behavior of cultured hair bulb papilla cells and root sheath fibroblasts
Testosterone and dihydrotestosterone slow hair cell growth, while estradiol has no effect.
research Hormonal profile in Indian men with premature androgenetic alopecia
Premature balding in some men may be linked to altered hormones, but it's not the male equivalent to polycystic ovary syndrome or metabolic syndrome.
research Finasteride inhibits epinephrine synthesis in humans: implication for sexual dysfunction
Finasteride may cause sexual dysfunction by reducing epinephrine levels.
research Intratesticular Control Of Steroidogenesis
The testes control steroid production through complex interactions involving various cells and signaling molecules.
research Low Anabolic Profile in Assessing a Patient’s Overall Hair Loss
Certain supplements, like whey protein isolate and growth hormones, can worsen hair loss.