136 citations
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May 2019 in “Cells” Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
113 citations
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September 2005 in “Journal of Investigative Dermatology” Applying a special compound can promote hair growth without harmful side effects.
89 citations
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November 2017 in “Journal of Cellular Physiology” The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
80 citations
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April 2017 in “Frontiers in Pharmacology” PDRN helps repair tissue and improve wound healing with a high safety profile.
57 citations
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March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.
56 citations
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November 2003 in “Journal of Investigative Dermatology” MMP-19 may worsen skin diseases by affecting skin growth and inflammation.
48 citations
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September 2017 in “Frontiers in Bioscience” Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.
45 citations
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March 2020 in “ACS Applied Materials & Interfaces” The new biomaterial inspired by ancient Chinese medicine effectively promotes hair growth and heals wounds in burned skin.
39 citations
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April 2019 in “Journal of Biomaterials Science, Polymer Edition” RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.
38 citations
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June 2019 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
36 citations
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August 2011 in “Journal of Controlled Release” Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.
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August 2021 in “npj Regenerative Medicine” Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
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February 2019 in “Genes” Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.
28 citations
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May 2000 in “Proceedings of the National Academy of Sciences” The Walleye dermal sarcoma virus cyclin causes excessive skin cell growth in mice.
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July 2017 in “European Journal of Dermatology” Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.
24 citations
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January 2019 in “Science China Life Sciences” Chitosan/LiCl composite scaffolds help heal deep skin wounds better.
23 citations
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May 2013 in “Virology” HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.
22 citations
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July 2015 in “PloS one” Foxp1 helps control hair stem cell growth and response to stress during hair growth cycles.
22 citations
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January 2014 in “Biological & Pharmaceutical Bulletin” Ginsenoside F2 may help prevent hair loss and promote hair growth better than finasteride.
21 citations
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July 2020 in “Stem Cell Research & Therapy” Fat stem cells from diabetic mice can still help heal wounds.
19 citations
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April 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
14 citations
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November 2019 in “Mediators of inflammation” IL-6 from stem cells helps repair skin and grow hair.
13 citations
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December 2024 in “Cellular and Molecular Life Sciences” Caspases do more than kill cells; they also help in cell growth and disease, and targeting them could lead to new treatments.
13 citations
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March 2017 in “Genomics” Genomic approach finds new possible treatments for hair loss.
12 citations
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July 2021 in “Scientific Reports” Glutamic acid helps increase hair growth in mice.
11 citations
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July 2021 in “Nanomaterials” Wound covers with α-13'-COOH from vitamin E can improve and speed up wound healing.
11 citations
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August 1997 in “Expert Opinion on Therapeutic Patents” Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
10 citations
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January 2019 in “Biomarker Insights” Scalp cooling to prevent hair loss from chemotherapy works for some but not all, and studying hair damage markers could improve prevention and treatment.
10 citations
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May 2018 in “Cell death discovery” HSP90 and lamin A/C are crucial for hair growth and could be targets for treating hair loss.
9 citations
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July 2020 in “Experimental Dermatology” Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.