October 2022 in “Journal of Kermanshah University of Medical Sciences” Different substances can affect how well the skin absorbs minoxidil, a hair loss drug. Caprylic acid helps the skin absorb it the best, followed by propylene glycol and water.
September 2022 in “Journal of pharmaceutical sciences” Thicker minoxidil solutions work better and need less frequent application.
June 2021 in “Journal of Pharmaceutical Care Anwar Medika” The hair tonic made from cayenne pepper leaf extract is physically stable and suitable for use.
January 2021 in “Indonesian Journal on Medical Science” The hair tonic with aloe vera and celery was successfully made, with the first formula being the most stable.
Aloe vera hair tonic with 10% and 15% concentrations effectively promoted hair growth in male rats.
Both 5% minoxidil solution and milky lotion effectively and safely treat male hair loss, with the lotion being a good alternative for those sensitive to certain ingredients.
January 2013 in “วารสารเภสัชศาสตร์อีสาน (Isan Journal of Pharmaceutical Sciences, IJPS)” Carthamus tinctorius floret extract is a safe hair growth promoter with good skin absorption.
September 2010 in “Reactions Weekly” A woman was allergic to 5% minoxidil, with stronger reactions to higher concentrations.
A man got an allergic skin reaction after using a 5% minoxidil solution for hair growth, suggesting it's important to check the ingredients of such solutions.
January 2004 in “Journal of Clinical Dermatology” A man got a skin allergy from using a hair growth product called minoxidil.
March 2002 in “Clin-Alert” In 2002, various drugs caused serious side effects, including vitamin B12 deficiency, heart issues, blindness, hypersexuality, allergic reactions, blood clotting problems, pupil dilation, capillary leak syndrome, muscle breakdown, hepatitis, skin reactions, and lupus.
June 1992 in “Inpharma Weekly” Patch testing with different solvents helps find the right minoxidil formulation for those with scalp allergies.
September 1987 in “International Journal of Dermatology” Dr. Baral observed that applying minoxidil can cause hair to grow in areas other than where it was applied.
February 2024 in “PubMed” The new minoxidil lotion using Aloplus Total is stable and can be mixed with other ingredients for treating hair loss.
November 2022 in “Asian Journal of Pharmaceutical Research” The hydrogel with Finasteride provides controlled, sustained drug release and improved bioavailability.
January 2021 in “Social Science Research Network” The optimized microemulsion with finasteride and cinnamon oil can effectively deliver the drug through the skin without using ethanol.
Finasteride-loaded microemulsions, made with cinnamon oil, Tween20, propylene glycol, and water, can help maintain stemness of dermal cells, potentially aiding in hair regeneration.
Niosomes improve aminexil's effectiveness in preventing hair loss without needing propylene glycol.
April 2025 in “Jurnal Inovasi Bahan Lokal dan Pemberdayaan Masyarakat” Varying propylenglycol affects the pH, specific gravity, and viscosity of wax apple leaf hair tonic, meeting Indonesian standards.
Azelaic acid and vitamin B6 together may improve hair growth.
2 citations
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May 2022 in “Journal of Industrial and Engineering Chemistry” Minoxidil-loaded nanoparticles effectively promote hair regrowth and are safe for use.
11 citations
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January 2006 in “Drug development and industrial pharmacy” Adding TPGS to minoxidil solutions can improve skin penetration and retention, especially in water and PEG 400-based solutions.
18 citations
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October 2005 in “International Journal of Pharmaceutics” Adding a small amount of TPGS to minoxidil can help hair growth, but too much TPGS reduces this effect and increases minoxidil in the blood.
58 citations
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December 2012 in “Aaps Pharmscitech” LCN may improve finasteride delivery for hair loss treatment.
February 2023 in “Ankara Üniversitesi Veteriner Fakültesi dergisi” Two calves died from ethylene glycol poisoning, a condition more common in pets.
130 citations
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January 2017 in “International journal of nanomedicine” Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.
202 citations
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August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
30 citations
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December 2019 in “PLoS ONE” The new delivery system improved raloxifene's skin absorption and effectiveness against cancer cells.
61 citations
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May 2014 in “International journal of pharmaceutics” Nanocrystals improve skin penetration and stability of caffeine, suggesting a new method for delivering similar substances through the skin.
100 citations
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June 2011 in “Journal of The American Academy of Dermatology” 5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.