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Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

New compounds may help treat prostate issues without affecting androgen receptors.

Targeting 5α-reductase type 1 may help manage Tourette-like symptoms.

Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.

Steroid hormones may affect sexual maturation in cod by altering certain KCa channel expressions.

5α-reductases increase epitestosterone's effect on androgen receptors.

Certain gene changes in osteopontin are linked to higher risk of atopic dermatitis and asthma.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

A substance called prostaglandin D2 is found more in bald scalps and it stops hair from growing. Blocking its receptor could potentially treat hair loss.

Certain genetic markers may increase or decrease prostate cancer risk.

Allopregnanolone may enhance alcohol's effects on dopamine neurons, influencing addiction risk.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

No genetic link between prostaglandins and hair loss found.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Shorter GGC triplet repeats in the androgen receptor gene are linked to less hair loss in Han men.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Researchers successfully made new compounds for hormone level tests, but one attempt led to an unexpected product, correcting a past error.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Researchers identified promising inhibitors for the BRD4 protein, including finasteride and amentoflavone.

RXR and RAR proteins in skin may help with cell growth, hair growth, and gland function.

Neurosteroids are crucial for stress response, and targeting specific receptors may help treat certain disorders.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

A certain gene variant may increase the risk of polycystic ovary syndrome in Chinese women.

Gene variant linked to prostate cancer, hormone levels, and hair loss.

PPAR β/δ is important for skin health and disease treatment, but more research is needed.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.