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Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

New compounds show promise as nonsteroidal treatments for hair loss.

The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.

The process effectively regenerates the Pd/C catalyst for finasteride synthesis.

Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.

Prostaglandin F2alpha and related compounds can increase hair growth and darken hair in mice.

New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Synthetic 19-norprogestins promote bone cell growth and function through their non-phenolic metabolites.

A compound from brown algae boosts the production of a certain inflammatory substance in skin cells.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

Adding cerium(III) chloride to Grignard reagents improves the making of compounds that could treat prostate issues and hair loss.

PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.

New steroid derivatives show promise as anticancer agents, even against resistant cells.

Phenylpropanoid sucrose esters show potential as anticancer agents.

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Canine hair follicle cells convert progesterone into various metabolites, mainly cortisol.

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

The new compound may be a safer alternative to finasteride for prostate protection.

Researchers created a new method to measure brain steroids, finding higher levels of certain steroids and changes due to a drug.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

New compounds show promise for treating benign prostate hyperplasia with fewer side effects.

Local estrogen synthesis in skin may improve wound healing.