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Finasteride effectively treats baldness but may cause sexual side effects.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Finasteride lowers risk of urinary issues and surgery by over 50% in 4 years.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

There is no clear recommendation for using selenium in cancer patients; it may be beneficial to correct low selenium levels before treatment.

Certain drugs that block specific enzymes can help treat prostate diseases.

Antiandrogens may help treat conditions like excessive hair growth, prostate tumors, male baldness, and acne by blocking male hormone effects.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Tamoxifen effectively treats gynecomastia without causing impotence.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Older men with severe symptoms and larger prostates should focus on prevention, using finasteride and alpha-blockers to manage acute urinary retention.

ADT for prostate cancer may harm the heart, but GnRH antagonists might be safer.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Cinnamomi cortex may help treat prostate enlargement by reducing related proteins.

Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.

Finasteride reduces PSA levels, terazosin doesn't affect them, and tracking prostate cancer in patients taking finasteride could be difficult.

Targeting ACE2 and TMPRSS2 may help prevent or treat COVID-19 in cancer patients.

New sulfur-containing steroid analogs show promise for more targeted medical treatments.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Epitestosterone may act as a weak antiandrogen and can inhibit an enzyme involved in testosterone metabolism.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Using finasteride with TIP extends time off period for prostate cancer patients.

Men with benign prostatic hyperplasia are more likely to have metabolic syndrome than those without it.