18 citations
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June 2021 in “Endocrinology” Anti-androgens might help reduce COVID-19 severity in men.
18 citations
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November 2012 in “Current opinion in urology” Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.
17 citations
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May 2019 in “Molecules” These temporary hair dyes may be harmful to human health.
1 citations
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January 2022 in “BMC Genomic Data” The study found that androgen receptors in skin cells mainly affect the focal adhesion pathway and control the caveolin-1 gene, with implications for new treatments for related diseases.
8 citations
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January 2024 in “Medical Principles and Practice” IGFBP5 may be a potential target for Parkinson's treatment by reducing neuron death.
13 citations
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June 2017 in “Biochimie open” All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.
June 2025 in “British Journal of Clinical Pharmacology” Chemotherapy often causes skin and hair issues, but early management can help improve patient care.
8 citations
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May 2025 in “Pharmaceuticals” In 2024, the FDA approved 27 innovative small-molecule drugs, with many offering significant treatment improvements.
5 citations
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November 2015 in “Journal of Enzyme Inhibition and Medicinal Chemistry” Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.
149 citations
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January 2011 in “Nature reviews. Urology” Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.
24 citations
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March 2020 in “Cells” Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.
1 citations
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April 2015 in “InTech eBooks” RAGE is a potential target for melanoma treatment, but its effectiveness is uncertain due to variable expression levels.
April 2026 in “The Open Biotechnology Journal” Resveratrol shows health benefits but faces challenges in effectiveness and regulation.
1 citations
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April 2023 in “International Journal of Molecular Sciences” Botryococcus terribilis Ethanol Extract may reduce inflammation by changing gene expression in cells.
49 citations
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November 2021 in “Annual review of pathology” Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
9 citations
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July 2024 in “Toxins” OnabotulinumtoxinA is used to treat wrinkles, pain, sweating, hair loss, and more by temporarily paralyzing muscles and affecting pain pathways.
7 citations
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December 2022 in “Plants” Guava leaf extract may help treat hair loss and protect cells by blocking certain genes and fighting damaging molecules.
1 citations
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February 2023 in “Plants” BB4CMU rice bran oil may help treat hair loss and gray hair.
December 2025 in “Current Issues in Molecular Biology” New steroid compounds may help with hormonal therapy and have potential benefits for glucose disorders, but more research is needed.
Ca²⁺-mediated protein citrullination controls cell growth in the CNS and may help treat brain tumors.
6 citations
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January 1996 in “Endocrine-related Cancer” Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.
59 citations
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October 2020 in “Stem Cell Reviews and Reports” Men have higher COVID-19 mortality rates than women due to biological and lifestyle factors.
68 citations
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April 2014 in “Journal of Molecular Endocrinology” The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.
8 citations
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June 2016 in “Clinical Chemistry” PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.
June 2023 in “Journal of multidisciplinary sciences (Online)” PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.
104 citations
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January 2016 in “Food & Function” Olive oil compounds may help prevent cancer in animals, but human results are mixed.
10 citations
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November 2019 in “Cold Spring Harbor Perspectives in Biology” Stem cells are more dynamic and adaptable than previously believed.
80 citations
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April 2018 in “Trends in Molecular Medicine” Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.
April 2010 in “The Journal of Urology” Human prostate cells produce more WISP1/CCN4 when there's not enough oxygen.
39 citations
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May 2010 in “Stem Cells” Ephrins slow down skin and hair follicle cell growth.