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Multitarget drugs are needed to better treat complex diseases.

Finasteride helps improve treatment for benign prostatic hyperplasia.

Skin-on-a-chip devices better mimic human skin for research.

A stable, active version of a growth factor was made in bacteria, showing promise for medical use.

Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.

Mutations in the AR gene cause hair thinning and loss.

Caffeine can boost health, prevent diseases, and improve performance, with new methods enhancing its benefits.

Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.

Finasteride doesn't improve survival in LNCaP tumor model during off-cycle of therapy.

The Hedgehog signaling pathway is linked to cancer development, and targeting it with inhibitors shows promise but faces challenges like resistance.

Dosing time affects finasteride's effectiveness and safety in rats.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Clinical trials should use innovative designs and biomarkers to improve precision therapy and patient outcomes.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

Combining different treatments may be needed to effectively manage chronic prostatitis.

Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

3D models and organoids improve liposarcoma research and therapy development.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.

New steroids were effective in blocking male hormone receptors in hamster prostates.

The letter is skeptical about the effectiveness of anti-androgen therapy for COVID-19 and calls for strong evidence from clinical trials.

PSA might help diagnose PCOS and related skin issues, but more research is needed.

Wearing a frozen glove during chemotherapy can reduce nail and skin problems but may not be comfortable for everyone.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.

The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.

Finasteride use may increase the risk of male breast cancer.

Antiandrogen therapy helps treat genetic hair loss.