research Anti-Androgenicity of Flutamide and its Metabolite Sch 16423
Flutamide and its metabolite can effectively reduce androgen effects.
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210-240 / 1000+ resultsresearch Cyproterone Acetate in the Treatment of Sexual Disorders: Pharmacological Base and Clinical Experience
Cyproterone acetate effectively treats sexual disorders by reducing sexual functions and is generally well-tolerated.
research The endocrinology of baldness
Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.
research Novel Synthetic Steroid Derivatives: Target Prediction and Biological Evaluation of Antiandrogenic Activity
New steroid compounds may help with hormonal therapy and have potential benefits for glucose disorders, but more research is needed.
research BPH: epidemiology and comorbidities.
BPH is common in older men and often occurs with other age-related health issues.
research 5alpha-reductase: history and clinical importance.
5alpha-reductase inhibitors like finasteride and dutasteride effectively treat BPH by reducing DHT, offering symptom relief and potential future uses.
research 12 Treatment of hirsutism with 5α-reductase inhibitors
New compounds may soon be tested to treat excessive hair growth in women.
research Effect of a novel steroid (PM-9) on the inhibition of 5α-reductase present in Penicillium crustosum broths
PM-9 and finasteride effectively inhibit the enzyme that converts testosterone to DHT.
research Common urologic diseases in older men and their treatment: how they impact fertility
Urologic diseases and treatments in older men can negatively affect fertility, and doctors should talk to patients about this.
research Adrenal steroid precursors exert potent androgenic action in the hamster sebaceous glands of flank organs and ears.
Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.
research Evolution, classification, structure, and functional diversification of steroid 5α-reductase family in eukaryotes
Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.
research The Double-Edged Proteins in Cancer Proteomes and the Generation of Induced Tumor-Suppressing Cells (iTSCs)
Tumor proteins can both promote and suppress cancer, depending on the situation.
research The Conception and Evaluation of Sexual Health Literature
The document concludes that better research methods are needed in men's sexual health to provide stronger evidence and improve patient care.
research Hemorrhagic Cystitis in Allogeneic Stem Cell Transplantation: A Role for Age and Prostatic Hyperplasia
Older age and prostatic hyperplasia in males increase the risk of hemorrhagic cystitis after stem cell transplantation.
research Identification of xenobiotics interfering with 5 α -reductase (SRD5A2) activity
MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.
research Penis Endocrinology
Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.
research Androgenic alopecia--Its characteristics and perspectives
Male pattern baldness is mainly caused by a hormone called dihydrotestosterone (DHT), and drugs that can block this hormone might help prevent hair loss.
research Androstenedione
Androstenedione, a hormone supplement, doesn't improve muscle or performance and can cause harmful side effects.
research Oral administration of low-dose bisphenol A promotes proliferation of ventral prostate and upregulates prostaglandin D2 synthase expression in adult rats
Low doses of BPA can increase prostate growth and change hormone levels in adult rats.
research Androgenetic alopecia at various ages and prostate cancer risk in an equal-access multiethnic case–control series of veterans
Early balding, especially frontal, increases prostate cancer risk; more research needed.
research Increased DHT levels in androgenic alopecia have been selected for to protect men from prostate cancer
Higher DHT in male baldness may protect against prostate cancer.
research Abiraterone and spironolactone in prostate cancer: a combination to avoid
Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.
research Prostate specific antigen (PSA) in diagnosis of polycystic ovarian syndrome – a new insight
PSA levels are higher in women with PCOS, but FAI is a more accurate marker for diagnosis.
research Hormonal treatment for male-pattern hair loss: implications for cancer of the prostate?
Finasteride treats hair loss but may affect prostate cancer detection.
research Rat steroid 5α-reductase kinetic characteristics: Extreme pH-dependency of the type II isozyme in prostate and epididymis homogenates
The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.
research Baldness, benign prostate hyperplasia, prostate cancer and androgen levels
The study found no link between baldness patterns and androgen levels in men with benign prostate enlargement or prostate cancer.
research Androgenic alopecia is not useful as an indicator of men at high risk of prostate cancer
Baldness at age 40 is not linked to a higher risk of aggressive prostate cancer.
research Age-Dependent Associations between Androgenetic Alopecia and Prostate Cancer Risk
Early balding at 40 increases prostate cancer risk.
research Androgenetic alopecia and polymorphism of the androgen receptor gene (SNP rs6152) in patients with benign prostate hyperplasia or prostate cancer
Hair loss gene linked to prostate issues.
research Androgenic alopecia may have evolved to protect men from prostate cancer by increasing skin exposure to ultraviolet radiation
Male pattern baldness might have evolved to help protect against prostate cancer by increasing UV radiation on the scalp.