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Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Long-term, low-dose finasteride may reduce the risk of benign prostatic hyperplasia and prostate cancer.

AKR1C3 could be a treatment target for metabolic issues in PCOS.

Shorter PSADT after prostate surgery is linked to higher risk of death.

Low dose finasteride causes only small changes in PSA levels in older men with BPH.

Epithelial stem cells can adapt and help in tissue repair and regeneration.

Adipose-derived stem cells are promising for tissue and organ repair due to their easy access and versatility.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Finasteride effectively treats baldness but may cause sexual side effects.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Adult tissue stem cells can adapt and switch roles to help repair and maintain the body.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

Vitamin D3 affects cell differentiation in specific skin areas.

The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Certain drugs that block specific enzymes can help treat prostate diseases.

Low doses of mixed chemicals cause permanent reproductive malformations in male rats.

Tamoxifen effectively treats gynecomastia without causing impotence.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Finasteride reduces prostate cancer risk but may affect ejaculatory volume and requires careful consideration for young men.

Men with benign prostatic hyperplasia are more likely to have metabolic syndrome than those without it.