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Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.

Capsaicin offers health benefits and flavor but faces challenges in food use.

Eating apples can help prevent heart disease, cancer, and other conditions because they have healthy plant chemicals.

EDA2R is a key gene linked to ageing and diseases, and targeting it may help treat conditions like hair loss and chronic diseases.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

Fewer GGC sequences in the androgen receptor gene improve finasteride treatment for hair loss.

RAGE is a potential target for melanoma treatment, but its effectiveness is uncertain due to variable expression levels.

Lifestyle changes and environmental strategies can help address declining testosterone levels.

Blocking androgen receptors boosts macrophages' ability to clear certain bacteria.

Fibroblast growth factors could be a better, safer treatment for hair loss than current options.

The guideline emphasizes a multidisciplinary approach and informed consent for gender-affirming hormone treatment, with regular follow-ups and individualized care.

Drug repositioning is a promising way to quickly develop new treatments, especially for rare diseases.

Understanding the Y chromosome is key to male health, aging, and developing diagnostic tools.

MicroRNAs could help assess and manage multiple chronic diseases.

Hydrogel composites have great potential in regenerative medicine, tissue engineering, and drug delivery.

Aesthetic rehabilitation techniques can improve life quality and wellbeing for disabled patients.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

Standardized procedures are crucial for collecting and preparing biological samples to ensure accurate clinical metabolomics results.

Local flaps are effective for covering small to large scalp and forehead defects with good cosmetic results.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

Hormone replacement therapy may lower the risk of severe COVID-19 outcomes in non-immunosuppressed people and male organ transplant recipients.

Certain genes and X chromosome patterns may significantly contribute to the development of hair loss.

A genetic test can identify people at risk of male pattern baldness early, allowing for quicker treatment.

Spironolactone may help reduce COVID-19 severity in men by blocking harmful effects of certain hormones.

Sex hormones affect liver fat and metabolic health differently in men and women.

Myotonic Dystrophy may age cells faster, and drugs that target aging could be potential treatments.

Prostate cancer is common, but risk can be reduced by avoiding smoking, unhealthy diet, inactivity, certain medications, and risky jobs.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Drugs that block DHT production can effectively treat enlarged prostate and improve urinary issues with some sexual side effects.