65 citations
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March 1999 in “Urology” Finasteride didn't significantly improve ICPPS symptoms, more research needed.
54 citations
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November 2001 in “Urology” The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.
53 citations
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June 1993 in “Proceedings of the National Academy of Sciences of the United States of America” LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
50 citations
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January 2016 in “The FEBS journal” RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.
46 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Disrupting Acvr1b in mice causes severe hair loss and thicker skin.
39 citations
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February 2011 in “The Prostate/The prostate” Some men's prostate tissues have low enzyme levels due to genetic changes, possibly affecting treatment for prostate enlargement.
33 citations
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January 2009 in “Journal of Cutaneous and Aesthetic Surgery” Finasteride reduces prostate cancer risk but may affect ejaculatory volume and requires careful consideration for young men.
27 citations
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January 1984 in “Pharmacology & Therapeutics” Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
24 citations
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October 2008 in “International Braz J Urol” Lovastatin doesn't improve lower urinary tract symptoms treatment.
16 citations
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October 2007 in “Andrologia” DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.
13 citations
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April 1994 in “Journal of Investigative Dermatology” Androgen receptors found in monkey scalps, similar to humans, affect hair growth.
11 citations
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September 2021 in “Journal of molecular endocrinology” ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
11 citations
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June 2020 in “Biomedicines” % free PSA and urinary markers help better identify prostate cancer.
10 citations
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October 2012 in “Andrology” Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.
9 citations
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May 2019 in “Experimental Cell Research” HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.
9 citations
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February 2018 in “Journal of Pharmaceutical and Biomedical Analysis” Quick, selective detection of tadalafil and finasteride in human plasma developed.
6 citations
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September 2017 in “Experimental and Therapeutic Medicine” Shortened PEDF peptides speed up skin wound healing by boosting cell growth.
4 citations
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March 2017 in “Al-Mi’galaẗ al-sa'udiyaẗ lī-ulum al-ḥayaẗ” Leonuri Herba alkaloids may help treat hormone-induced enlarged prostate in rats.
2 citations
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March 2019 in “American journal of physiology. Renal physiology./American journal of physiology. Renal physiology” New treatments targeting fibrosis could improve urinary symptoms in BPH.
2 citations
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September 2017 in “Archives of Medical Science” Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.
1 citations
,
January 2022 in “European Journal of Pharmacology” Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.
1 citations
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March 2021 in “F1000Research” Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.
1 citations
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October 2020 in “The Egyptian Journal of Histology” Ginseng was more effective than finasteride in treating enlarged prostate in rats.
December 2025 in “Doğu Fen Bilimleri Dergisi” Vimentin, desmin, and laminin help maintain rat skin structure.
November 2025 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin” Sporadic trichoblastic neoplasms generally don't recur or spread, with one case showing a specific genetic fusion.
November 2025 in “Cancers” Men with male pattern baldness may have a slightly higher risk of prostate cancer.
May 2024 in “KIU journal of health science” Kolaviron and quercetin may help treat prostate issues.
June 2021 in “F1000Research” Plant-based compounds may offer safer prostate cancer treatment with fewer side effects.
October 2015 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” Finasteride reduces prostate size and PSA levels in young men with hair loss.
February 2013 in “Journal of The American Academy of Dermatology” Hair loss is a common, often overlooked side effect of hormone treatments for breast and prostate cancer.