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Gender-affirming hormone treatments need better patient-focused outcome measurements and standardized data collection.

5-alpha-reductase inhibitors lower PSA density but higher PSA density indicates disease progression.

The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.

The study explored a possible link between finasteride use and suicide.

5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.

Most men with lichen planopilaris had it confirmed by biopsy and often had thyroid issues, sexual dysfunction, or prostate cancer, hinting at a link with hormonal problems.

Finasteride and dutasteride reduce prostate cancer risk, but finasteride may increase higher-grade cancer risk.

Extending androgen suppression before radiotherapy offers no extra survival benefit for intermediate-risk prostate cancer.

New skin lesions on the scrotum or vulva in patients with a history of internal cancer could indicate rare skin metastasis.

Hair loss is a common, often overlooked side effect of hormone treatments for breast and prostate cancer.

Hair loss is a common but often unreported side effect of cancer treatments, especially for breast and prostate cancers.

Hair loss is a common side effect of hormone treatments for cancer.

Finasteride is effective for hair loss but has controversial side effects.

Breast cancer survivors may have a higher risk of falls, tamoxifen could prevent breast cancer and deaths, new guidelines urge caution with prostate cancer therapy, and early balding in men may indicate a higher prostate cancer risk.

20(S)-Protopanaxadiol-aglycone may help prevent and treat prostate cancer by reducing androgen receptor activity.

Higher C-peptide levels in African-American men and higher HbA1c levels in Caucasian men are linked to lower PSA levels.

Low-dose finasteride lowers PSA levels, which can make prostate cancer harder to detect.

The trial on testosterone replacement therapy in older men faced concerns due to prostate cancer risk.

Androstenedione, a hormone supplement, doesn't improve muscle or performance and can cause harmful side effects.

Finasteride is effective for male hair loss, but it may cause fertility issues, mental health problems, and rarely, breast growth. Regular health checks can reduce the risk of prostate cancer. Patient understanding and involvement in treatment is important.

DA-9401 protects against hair loss, improves organ function, and prevents infertility caused by finasteride.

Finasteride's link to health issues like male breast cancer, infertility, and prostate cancer needs more research through placebo-controlled trials to confirm.

Six new risk spots for early hair loss were found, which also link to Parkinson's disease and lower fertility. Two genes, FOXA2 and HDAC4, could be new treatment targets. Hair loss might also be connected to heart disease, metabolic syndrome, and prostate cancer.

Fiber implants effectively treat permanent hair loss with few complications.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Finasteride safely lowers DHT levels without affecting testosterone.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Finasteride may cause long-lasting sexual side effects.

5α-reductase inhibitors may cause persistent sexual dysfunction and depression, needing more research on long-term effects.

Dual therapy with specific medications can help manage male urinary symptoms and reduce side effects.