MFN2 mutations cause mitochondrial problems, unusual fat distribution, and low leptin despite high body fat.
2 citations
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August 2004 in “Veterinary Dermatology” A dog with a hereditary skin condition causing blisters and hair loss survived for a year.
488 citations
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July 2021 in “Cell” Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
122 citations
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January 2006 in “Molecular & Cellular Proteomics” Human hair contains many proteins, with some being highly abundant and modified.
82 citations
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October 2019 in “Frontiers in Immunology” Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.
37 citations
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May 2018 in “Frontiers in physiology” Certain RNA molecules are important for the development of wool follicles in sheep.
26 citations
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March 2020 in “Antioxidants” Microwave-assisted Opuntia humifusa extract protects skin cells from pollution damage.
19 citations
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January 2019 in “Animals” PDGFA helps activate hair growth in cashmere goats.
17 citations
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March 2022 in “BMC Genomics” Cashmere fiber diameter in Tibetan goats is influenced by their stress, oxygen, and metabolic adaptations.
16 citations
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April 2021 in “Frontiers in Cell and Developmental Biology” New hair follicles could be created to treat hair loss.
16 citations
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November 2020 in “International journal of pharmaceutics” Using longer PEG chains helps nanoparticles penetrate hair follicles better, improving drug delivery for conditions like alopecia.
4 citations
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November 1968 in “Textile research journal” Hair fibers may have a unique, non-protein sheath not previously identified.
1 citations
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September 2025 in “Physiologia” Ovalbumin–aluminum sensitization causes increased pain sensitivity and nerve changes in mice.
April 2024 in “International journal of molecular sciences” Dermal factors are crucial in regulating melanin production in skin.
June 2023 in “Frontiers in Bioengineering and Biotechnology” The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.
February 2023 in “Journal of Ginseng Research/Journal of ginseng research” New ginseng compounds may help treat degenerative diseases.
21 citations
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October 2017 in “Cell death and disease” Sesn2 protects inner ear hair cells from damage by regulating certain cell survival pathways.
146 citations
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January 2004 in “Hormones” Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
139 citations
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December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” K6hf is a unique protein found only in a specific layer of hair follicles.
65 citations
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August 2013 in “Acta Biomaterialia” The new matrix improves skin regeneration and graft performance.
56 citations
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March 2015 in “Journal of Investigative Dermatology” Healthy mitochondria in skin cells are essential for proper hair growth and skin cell interaction in mice.
56 citations
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March 2003 in “Journal of Investigative Dermatology” 17β-estradiol can reduce inflammation in the skin.
52 citations
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October 2007 in “Molecular Therapy” Injecting lentiviral vectors into early gestation mice effectively targets skin stem cells for potential gene therapy.
49 citations
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September 2016 in “Genes Brain & Behavior” Zfp462 deficiency in mice causes anxiety-like behaviors and excessive self-grooming.
49 citations
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August 2004 in “The FASEB Journal” Mice with human skin protein K8 had more skin problems and cancer.
39 citations
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February 1990 in “The journal of cell biology/The Journal of cell biology” Trichohyalin, a hair follicle protein, has a part with repeating patterns of 23 amino acids.
35 citations
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January 2022 in “Clinical Infectious Diseases” Healthcare workers with COVID-19 reported more long-term symptoms, and physical activity may help reduce some of these symptoms.
32 citations
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June 2013 in “Journal of Investigative Dermatology” Mice without certain skin proteins had abnormal skin and hair development.
31 citations
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October 2019 in “Genes & Diseases” Basal cell carcinomas and squamous cell carcinomas have different gene activity patterns, suggesting unique treatment approaches.
20 citations
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December 2020 in “Frontiers in Immunology” The immune processes causing VKH and vitiligo are similar in dogs and humans.