research Protein degradation: expanding the toolbox to restrain cancer drug resistance
Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
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research De novo designed bifunctional proteins for targeted protein degradation
Newly designed proteins can effectively degrade specific proteins in cells, offering a promising alternative for targeted protein degradation.
research Proteolysis‐targeting chimeras in cancer therapy: Targeted protein degradation for next‐generation treatment
PROTACs offer a new, precise way to treat cancer by breaking down harmful proteins.
research De novo designed bifunctional proteins for targeted protein degradation
Newly designed proteins can effectively degrade specific proteins in cells, offering a potential new therapy method.
research Recent Advances in Peptide Drug Discovery: Novel Strategies and Targeted Protein Degradation
Peptide drugs now target hard-to-reach proteins more effectively and specifically.
research Emerging Strategies in Smart Nano-PROTAC for Stimuli-Responsive Protein Degradation and Precision Cancer Therapy
Smart nano-PROTACs improve cancer treatment by targeting proteins more precisely and reducing side effects.
research Peptide-Based PROTACs: Transitioning from Static Paradigm to a Dynamic Landscape within Targeted Protein Degradation
Peptide-based PROTACs show promise in targeting hard-to-treat proteins, especially for cancer therapy.
research Characterization of Soluble Protein Extracts from Keratinized Tissues: identification of Ubiquitin Universally Distributed in Hair, Nail, and Stratum Corneum
Ubiquitin, a protein, is found in hair, nails, and skin.
research Autophagy Controls the Protein Composition of Hair Shafts
Autophagy changes the protein makeup of hair.
research 1430 Autophagy controls the protein composition of hair shafts
Autophagy is important for determining the protein makeup of hair.
research Resistance Training Ameliorates Finasteride-Induced Disturbance in Protein Homeostasis in Skeletal Muscle of Rats
Resistance exercise can reduce muscle protein issues caused by finasteride.
research An Electron Microscopy Study of Keratin Degradation by the Fungus Microsporum gypseum in vitro
Microsporum gypseum fungus breaks down keratin in hair by digesting it enzymatically, starting with less keratinized parts.
research Crystallin Fusion Proteins Improve the Thermal Properties of Hair
Fusion proteins can protect hair from heat damage.
research The Mixed Lineage Kinase Leucine-Zipper Protein Kinase Exhibits a Differentiation-Associated Localization in Normal Human Skin and Induces Keratinocyte Differentiation upon Overexpression
ZPK helps skin cells mature and may affect skin health.
research Experimental study on the compatibility and degradation of human hair keratin bridging for peripheral nerve defects
Human hair keratin can help nerve regeneration and is a promising material for nerve repair.
research The effect of various cosmetic pretreatments on protecting hair from thermal damage by hot flat ironing.
Polymeric pretreatments can significantly reduce hair breakage and damage from hot flat irons.
research Comparative Proteomic Analysis in Scar-Free Skin Regeneration in Acomys cahirinus and Scarring Mus musculus
The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
research Identification of compound heterozygous mutations in AP1B1 leading to the newly described recessive keratitis–ichthyosis–deafness (KIDAR) syndrome
Mutations in the AP1B1 gene cause a new syndrome with skin, hearing, and developmental issues.
research Molecular elements of the regulatory control of keratin filament modulator AHF/trichohyalin in the hair follicle
The study concluded that a protein important for hair strength is regulated by certain molecular processes and is affected by growth phases.
research Tailored Effects of Plasma-Activated Water on Hair Structure Through Comparative Analysis of Nitrate-Rich and Peroxide-Rich Formulations Across Different Hair Types
Peroxide-rich plasma-activated water is gentler on hair than nitrate-rich formulations.
research Recovery and protection of photo‐damaged hairs with keratin‐encapsulated cationic liposomes
Keratin-encapsulated liposomes effectively repair and protect UV-damaged hair.
research Research Progress in Composition, Classification and Influencing Factors of Hair
Lipids are important for healthy hair, but their exact role is not fully understood and needs more research.
research Oxidative Modification in Human Hair: The Effect of the Levels of Cu (II ) Ions, UV Exposure and Hair Pigmentation
Reducing copper (II) ion levels in hair can decrease hair damage.
research 저항훈련은 랫 골격근에서 finasteride에 의해 유도된 단백질 항상성 교란을 개선시킨다
Resistance exercise helps improve muscle protein balance disrupted by finasteride.
research The physical and chemical disruption of human hair after bleaching – studies by transmission electron microscopy and redox proteomics
Bleaching hair causes severe structural and chemical damage, including protein loss and oxidation.
research Impact of oxidative hair coloring and bleaching on hair fiber properties
Bleaching damages hair the most, while dyes improve combability but still cause protein loss.
research Application of an Enzymatic Method for Identifying Hair Treatments
The enzymatic method can effectively identify chemical treatments on hair.
research Impact of ultraviolet radiation‐induced damage to hair fiber integrity: A multi‐technique physicochemical characterization of surface and cortex properties
UV radiation damages hair similar to bleaching, but double bleaching causes more severe protein degradation.
research LB1081 Three-dimensional imaging of tight junction-network across multiple layers of human epidermis by array tomography using backscattered electron-mode scanning electron microscopy
The study found that tight junctions reach the top layer of the skin's stratum granulosum, not just the second top layer as previously thought.
research Skin metabolism in obesity: A narrative review
Obesity harms skin health by causing inflammation and delayed wound healing.