282 citations
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April 2007 in “Journal of Agricultural and Food Chemistry” Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.
222 citations
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January 2005 in “Endocrine journal” Melatonin is important for skin health and protection, and can be made by the skin or applied to it.
211 citations
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May 2013 in “Journal of Nutrition Health & Aging” MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.
102 citations
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July 2007 in “Genes & Development” A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.
89 citations
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November 2014 in “Medical Clinics of North America” Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.
70 citations
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March 2010 in “The Journal of Steroid Biochemistry and Molecular Biology” Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.
60 citations
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June 2017 in “IOSR Journal of Pharmacy (IOSRPHR)” Carrots are nutritious and offer many health benefits, including antioxidant and anti-inflammatory effects.
58 citations
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June 2018 in “Scientific reports” Researchers found 15 new genetic links to skin traits in Japanese women.
53 citations
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October 2014 in “Free radical biology & medicine” Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.
50 citations
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May 2019 in “Drugs” Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.
50 citations
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December 2013 in “Stem Cells” Stem cell niches are adaptable and key for tissue maintenance and repair.
46 citations
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March 2019 in “Journal of Pineal Research” Melatonin improves cashmere goat hair growth and quality by increasing antioxidants and reducing cell death.
46 citations
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May 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.
41 citations
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September 2011 in “Journal of Ethnopharmacology” Panax ginseng extract helps mice grow hair.
40 citations
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December 2016 in “Journal of Ovarian Research” Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.
40 citations
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July 2015 in “Journal of Cellular Biochemistry” Cysteine helps maintain keratin production in skin cells even when iron is low.
39 citations
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June 2013 in “Journal of Cosmetic Dermatology” Herbal extracts and platelet-rich plasma together may help increase hair growth by making certain cells grow more, through specific cell growth pathways.
39 citations
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December 2011 in “PLoS ONE” Radiofrequency exposure can stimulate hair growth by increasing IGF-1 in hair follicle cells.
36 citations
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August 2011 in “Journal of dermatological science” Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.
27 citations
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March 2024 in “Frontiers in Pharmacology” Natural products can help overcome cancer drug resistance.
27 citations
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February 2020 in “Journal of Cardiovascular Translational Research” Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.
26 citations
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February 2002 in “Urologic clinics of North America” The document concludes that it's important to understand the placebo effect when evaluating the effectiveness of treatments in medical trials.
26 citations
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April 1984 in “The American Journal of Surgery” Gastric exclusion surgery caused major weight loss and health improvements but led to some anemia and vitamin deficiencies.
23 citations
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January 2020 in “Frontiers in Pharmacology” Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.
22 citations
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September 2018 in “Medical Clinics of North America” Facial aging is caused by natural processes and external factors, and can be managed with preventative measures and a variety of treatments tailored to individual needs.
21 citations
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May 2017 in “International Journal of Dermatology” Overweight smokers have worse hair loss.
19 citations
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July 2018 in “Mechanisms of Ageing and Development” Eating less can slow aging and help keep stem cells healthy by cleaning out damaged cell parts.
19 citations
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September 2010 in “The American journal of pathology” High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.
18 citations
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September 2017 in “Clinics in Dermatology” Obesity is linked to various skin disorders, which can help with early diagnosis and prevention of long-term health issues.
18 citations
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January 2013 in “Postepy Dermatologii I Alergologii” Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.