research Differentiation of nestin-negative human hair follicle outer root sheath cells into neurons in vitro
Human hair follicle cells can be turned into neural stem cell-like cells, which might help treat brain diseases.
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210-240 / 1000+ results research Mechanism of JmjC-containing protein Hairless in the regulation of vitamin D receptor function
Hairless protein helps control hair growth by regulating vitamin D receptor activity.
research The Double-Edged Proteins in Cancer Proteomes and the Generation of Induced Tumor-Suppressing Cells (iTSCs)
Tumor proteins can both promote and suppress cancer, depending on the situation.
research Transcriptome Analysis of Improved Wool Production in Skin-Specific Transgenic Sheep Overexpressing Ovine β-Catenin
Genetically modified sheep with more β-catenin grew more wool without changing the wool's length or thickness.
research Poly(rC) binding protein 2 acts as a negative regulator of IRES-mediated translation of Hr mRNA
A protein called PCBP2 controls the production of a hair growth protein by interacting with its genetic message and is linked to hair loss when this control is disrupted.
research Region-specific reversal of epidermal planar polarity in the rosette fancy mouse
Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.
research Stem Cells and their Niches
The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
research Tensile properties of twisted hair fibers
Twisting hair weakens it, but strength can be recovered at low twist levels.
research Screening of Protein Related to Wool Development and Fineness in Gansu Alpine Fine-Wool Sheep
Key proteins and pathways are crucial for wool fineness, but more research is needed.
research Case report: A novel splice-site mutation of MTX2 gene caused mandibuloacral dysplasia progeroid syndrome: the first report from China and literature review
A new MTX2 gene mutation caused a severe genetic disorder in a young Chinese girl.
research Keratinocytes of the Upper Epidermis and Isthmus of Hair Follicles Express Hemoglobin mRNA and Protein
Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.
research Abstracts
New treatments and diagnostic methods for various animal skin conditions showed promising results.
research 616 Endoplasmic reticulum stress upregulates NKG2D ligands in the hair follicle
Stress in hair follicle cells increases certain immune-related proteins, which might contribute to hair loss conditions.
research 195 Androgen action and 3D culture conditions influence dermal papilla cells inductive properties: the role of Wnt agonists/antagonists balance
DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.
research Peer Review #2 of "Human hair shaft proteomic profiling: individual differences, site specificity and cuticle analysis (v0.1)"
The research found that people's hair proteins vary, especially by ethnicity and body part, which could help identify individuals in forensic science.
research Peer Review #1 of "Human hair shaft proteomic profiling: individual differences, site specificity and cuticle analysis (v0.1)"
The research found that people's hair proteins vary by individual and body part, with some differences between ethnic groups, which could help in forensics.
research Human hair keratin hydrogel : fabrication, characterization and application
Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.
research 851 The role of astrotactin2 in regulating mammalian skin polarity
Astrotactin2 affects hair follicle orientation and skin cell polarity.
research A protein kinase target of a PDK1 signalling pathway is involved in root hair growth in Arabidopsis
AGC2-1 protein is essential for root hair growth in Arabidopsis.
research Transforming growth factor-β in stem cells and tissue homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research Hairless triggers reactivation of hair growth by promoting Wnt signaling
The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.
research Cell death in the skin
Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
research Review of Hair Follicle Dermal Papilla cells as in vitro screening model for hair growth
Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
research Studies on the Proteome of Human Hair - Identification of Histones and Deamidated Keratins
Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.
research Brg1 Governs a Positive Feedback Circuit in the Hair Follicle for Tissue Regeneration and Repair
Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.
research Thehairless gene of the mouse: Relationship of phenotypic effects with expression profile and genotype
Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.
research Wnt signaling: the good and the bad
Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
research Male reproductive health after 3 months from SARS-CoV-2 infection: a multicentric study
COVID-19 temporarily affects male reproductive health, but sperm and testosterone levels generally return to normal after three months.
research Influence of feed restriction on the wool proteome: A combined iTRAQ and fiber structural study
Feed restriction in sheep leads to finer wool fibers but may reduce wool quality.
research The development of several organs and appendages is impaired in mice lacking Sp6
Mice without the Sp6 gene have problems developing several body parts, including hair, teeth, limbs, and lungs.