211 citations
,
April 2018 in “Cold Spring Harbor Perspectives in Biology” Keratins are crucial for cell structure, growth, and disease risk.
55 citations
,
January 2013 in “International Journal of Cosmetic Science” African hair's keratin structure is influenced by its higher lipid content.
34 citations
,
February 2012 in “American Journal of Dermatopathology” Calretinin can help identify certain skin structures and tumors.
13 citations
,
July 2017 in “Biopolymers” Recombinant keratins can form useful structures for medical applications, overcoming natural keratin limitations.
April 2017 in “The Journal of urology/The journal of urology” SHH protein helps nerve regeneration in hypertensive rats.
October 2005 in “Nature reviews. Molecular cell biology (Print)” Hairless protein is key for hair growth, cell differences cause gene expression variation, and the N-end rule pathway senses nitric oxide for protein breakdown.
67 citations
,
February 1994 in “Developmental dynamics” Specific proteins and molecules play key roles in the development of human hair follicles.
4 citations
,
September 2004 in “Experimental Dermatology” Mutations in certain skin proteins cause severe skin issues, while others have limited effects, highlighting the need to understand these proteins for better treatments.
2 citations
,
April 2022 in “PLoS ONE” Vibration treatment may reduce migraine pain by changing cell structures.
1 citations
,
October 2022 in “JCI insight” Deleting the BRD4 protein in certain skin cells causes hair loss and skin inflammation.
July 2025 in “Underline Science Inc.” ROS influences the growth and structure of Arabidopsis root hairs.
June 2025 in “Biomolecules” RORA affects hair follicle stem cells' structure and movement, potentially helping treat hair loss.
November 2023 in “Advanced Science” A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” The hexosamine pathway helps maintain healthy skin by affecting the skin's structure and possibly increasing hair follicle stem cells.
19 citations
,
March 2013 in “Biology Letters” Early tetrapod keratins evolved into toe pad proteins in amphibians and hair proteins in mammals.
15 citations
,
May 2010 in “International Journal of Cosmetic Science” The cell membrane complex in mammalian hair has three distinct types with different structures and chemical properties.
36 citations
,
February 2006 in “Biochemical and Biophysical Research Communications” Wnt-10b helps skin cells develop into hair-related structures.
23 citations
,
June 2010 in “Journal of Investigative Dermatology” A mutation in the Soat1 gene causes hair structure defects and other health issues in AKR/J mice.
13 citations
,
April 2019 in “iScience” EGFR helps control how hair grows and forms without needing p53 protein.
10 citations
,
November 2020 in “American Journal Of Pathology” Integrin β1 is crucial for liver structure and function, preventing fibrosis.
8 citations
,
September 2016 in “Journal of Investigative Dermatology” Mice with more Flightless I protein grew back their claws better after amputation.
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
38 citations
,
February 1988 in “Molecular and Cellular Biology” Only one of the two K16 genes on chromosome 17 makes a functional protein for keratin filaments.
23 citations
,
February 2015 in “International Journal of Molecular Sciences” Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.
14 citations
,
May 2022 in “Stem cell reports” The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.
7 citations
,
January 2010 in “Animal” Angora goat hair grows faster and produces more protein than cashmere goat hair, and certain hormones and nutrients positively affect hair growth and protein synthesis.
September 2021 in “Research Square (Research Square)” Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.
18 citations
,
August 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Two existing drugs may help treat COVID-19 by inhibiting a key viral protein.
1 citations
,
May 2015 in “Experimental Dermatology” Overactive Stat3 in mouse skin causes hair loss and cell structure damage.
May 2006 in “The Journal of Cell Biology” Keratin 17 is crucial for cell growth in wound healing by aiding protein synthesis.