May 2025 in “Frontiers in Pharmacology” New treatments are needed for non-scarring alopecia due to current limitations.
January 2025 in “British Journal of Dermatology” Long scalp hair evolved for cooling and social signaling.
November 2024 in “Aging Cell” Removing senescent cells can improve hair growth and regeneration.
February 2024 in “International Journal of Molecular Sciences” Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.
September 2023 in “Biomedical Optics Express” New imaging techniques show testosterone delays hair growth and shrinks follicles in mice, but have limited depth for viewing.
November 2018 in “Journal of Investigative Dermatology” Lichen Planopilaris causes irreversible hair loss due to immune attacks on hair stem cells, but modulating PPAR-γ might help treat it.
Stem cell treatments show promise for hair loss but need more research.
27 citations
,
May 2019 in “Cosmetics” The hair cuticle is made of tough proteins that protect the hair, but more research is needed to fully understand its structure.
13 citations
,
April 2018 in “Scientific Reports” The genes KRT25 and SP6 affect curly hair in horses, with KRT25 also causing hair loss. If both genes are mutated, the horse gets curly hair and hair loss. KRT25 can hide the effect of SP6.
4 citations
,
June 2023 in “Journal of developmental biology” The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
18 citations
,
August 2014 in “Lipids” Human hair has more unsaturated fats inside than on the surface, and certain lipids may help bind the outer and inner layers together.
42 citations
,
April 2008 in “Acta materialia” Different ethnicities and treatments affect human hair strength and structure.
33 citations
,
November 2006 in “Survey of Ophthalmology” Madarosis is the loss of eyelashes and eyebrows due to various health issues and requires thorough examination to diagnose and treat the underlying cause.
29 citations
,
February 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Loss of Fz6 disrupts hair follicle and associated structures' orientation.
The document concludes that Loose Anagen Hair Syndrome is a benign condition where hair is thin and easily pulled out, often improving with age.
1 citations
,
January 2018 in “Springer eBooks” The document concludes that scalp cooling and treatments like minoxidil can help manage hair loss from cancer therapy.
214 citations
,
March 1993 in “Archives of Dermatology” Telogen effluvium is a reversible hair loss condition that requires a detailed diagnosis and often resolves on its own.
16 citations
,
October 2012 in “British Journal of Dermatology” Chemotherapy can cause significant hair thinning and changes in hair texture, while tamoxifen has a smaller effect.
418 citations
,
September 2012 in “Nature” African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.
November 2014 in “Elsevier eBooks” Gene mutations can cause problems in male genital development.
52 citations
,
January 2005 in “International journal of experimental pathology” Melatonin may reduce skin damage caused by X-rays in rats.
46 citations
,
January 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.
25 citations
,
May 2018 in “Clinical & Translational Oncology” New melanoma treatments can cause skin side effects, including skin cancer and rashes, but combining treatments may reduce these risks.
19 citations
,
December 2001 in “Dermatologic Therapy” Horizontal scalp biopsy sections are better for diagnosing alopecia areata, showing fewer hair follicles and more miniaturized hairs.
18 citations
,
June 2017 in “Proceedings of the National Academy of Sciences of the United States of America” A gene called Gk5 controls lipid production in the skin and affects hair growth.
1 citations
,
August 2013 in “Springer eBooks” Birth control pills and anti-androgen medications help manage hair growth, acne, and hair loss in women with PCOS.
47 citations
,
May 2012 in “Wiley Interdisciplinary Reviews-Developmental Biology” The conclusion is that understanding how feathers and hairs pattern can help in developing hair regeneration treatments.
January 2014 in “HAL (Le Centre pour la Communication Scientifique Directe)” Sex hormones affect dog skin conditions, but more data is needed.
February 2026 in “International Journal of Surgery Case Reports” Bezoars can cause serious digestive issues and need early imaging and surgery for effective treatment.
69 citations
,
February 2008 in “The American journal of pathology” Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.