August 2025 in “Research Square (Research Square)” High TNF-α levels may increase hair loss risk after PRP therapy.
Human scalp hair follicles have PGE2 and its receptors, which might affect hair growth.
29 citations
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January 2018 in “International Journal of Trichology” PRP treatment helps hair growth and density with 70.7% success, but more research needed.
Platelet-rich plasma improves skin and hair growth in newborn mice.
August 2021 in “Indian dermatology online journal” A young boy with a rare skin and nail condition improved significantly with simple topical treatments.
15 citations
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August 2019 in “Dermatologic Therapy” Platelet-rich plasma (PRP) may help treat hair loss in patients with frontal fibrosing alopecia who don't respond to other treatments.
July 2025 in “JOJ Dermatology & Cosmetics” Both treatments improved hair quality and thickness equally, with mild side effects.
October 2019 in “Tishreen University Journal -Medical Sciences Series” Platelet-rich plasma (PRP) injections in the scalp are effective for treating male pattern baldness.
9 citations
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September 2024 in “Frontiers in Endocrinology” Platelet-rich plasma infusion improved pregnancy outcomes for women with thin endometrium.
October 2020 in “Medical journal of Tabriz University of Medical Sciences and Health Services” PRP injections significantly increased hair growth in patients with androgenic alopecia.
2 citations
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September 2022 The PER3 rs772027021 SNP may cause mild skin pigmentation changes in a new subtype of dyschromatosis universalis hereditaria.
November 2025 in “Northern International Medical College Journal” PRP injections can effectively improve knee osteoarthritis symptoms.
2 citations
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March 2020 in “Plastic and Reconstructive Surgery” The book provides guidelines for using PRP and microneedling in skin treatments, despite limited scientific data.
15 citations
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May 2017 in “Journal of Cellular Biochemistry” The hairless protein is important for skin, hair, and may influence cancer development.
September 2024 in “Revista Foco” Platelet-Rich Plasma (PRP) is a safe and effective tool for facial rejuvenation and scar treatment.
March 2026 in “Journal of Enzyme Inhibition and Medicinal Chemistry” PROTACs show promise in cancer treatment by effectively degrading specific harmful proteins.
11 citations
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May 1996 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.
13 citations
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June 2020 in “Plastic and reconstructive surgery. Global open” PRP preservation improves hair transplant results better than saline.
6 citations
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June 2021 in “Developmental biology” Dermal EZH2 controls skin cell development and hair growth in mice.
September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.
6 citations
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January 2020 in “International journal of biological sciences” Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.
September 2015 in “Hair transplant forum international” Platelet Rich Plasma may help treat hair loss, but more detailed research is needed to confirm its effectiveness.
19 citations
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May 2006 in “Clinical and Experimental Dermatology” Researchers found a new mutation causing total hair loss from birth.
41 citations
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June 2010 in “Journal of Investigative Dermatology” New cells are added to the hair's dermal papilla during the active growth phase.
25 citations
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November 2018 in “Cell reports” The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.
The combination of minoxidil, microneedling, and PRP is more effective for hair growth than minoxidil alone.
7 citations
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December 2015 in “International Journal of Dermatology” New and known mutations in the hairless gene cause a hair loss condition called Atrichia with papular lesions.
124 citations
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November 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.
5 citations
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September 2024 in “Dermatological Reviews” More research and collaboration are needed to effectively use PRP, stem cells, and exosomes in medicine.
July 2021 in “PARIPEX INDIAN JOURNAL OF RESEARCH” PRP injections significantly improve hair regrowth in alopecia areata.