15 citations
,
April 2016 in “Hormones” Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.
24 citations
,
July 1979 in “Archives of Dermatology” Patients with renal disease may develop vitamin A toxicity even with low-dose supplements.
May 2021 in “Journal of the Endocrine Society” A woman's severe hormone imbalance after menopause led to finding a rare ovarian tumor, treated by surgery.
November 2014 in “Elsevier eBooks” Gene mutations can cause problems in male genital development.
15 citations
,
October 2014 in “Hormone Molecular Biology and Clinical Investigation” Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.
19 citations
,
June 2021 in “The world journal of men's health” Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.
Neonatal allopregnanolone and stress affect behavior differently in adolescence and adulthood.
July 2026 in “Frontiers in Endocrinology” A young girl had a hormone-secreting tumor removed, leading to decreased hormone levels, but ongoing monitoring is needed.
April 2020 in “BMC endocrine disorders” A woman with childhood growth hormone deficiency had multiple hormone deficiencies and developed serious lung and kidney problems later in life.
32 citations
,
September 2010 in “Stress” Neurosteroids help protect fetal brains from asphyxia damage.
81 citations
,
July 2008 in “The Journal of Clinical Endocrinology and Metabolism” Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
4 citations
,
March 2017 in “Al-Mi’galaẗ al-sa'udiyaẗ lī-ulum al-ḥayaẗ” Leonuri Herba alkaloids may help treat hormone-induced enlarged prostate in rats.
October 2020 in “Medicine - Programa De Formación Médica Continuada Acreditado” Female hyperandrogenism is a condition caused by too much male hormones, leading to skin issues and ovulation problems, often due to Polycystic Ovary Syndrome, and is treated based on individual symptoms.
January 2007 in “Annals of The Royal College of Surgeons of England” Removing a hormone-producing adrenal tumor can stop hair loss in women with high testosterone levels.
May 2021 in “Journal of the Endocrine Society” A woman with a rare ovarian tumor and hyperparathyroidism improved after surgery, highlighting the need for reporting unusual cases to understand and manage rare diseases.
August 2024 in “Latin American Journal of Development” 5α-reductase enzymes are crucial in certain disorders, and while treatment advances exist, more research on SRD5A3 is needed.
1 citations
,
April 1993 in “Problemy e̊ndokrinologii” Spironolactone effectively reduces symptoms of hyperandrogenism like hirsutism and acne.
June 2023 in “Clinical Chemistry” Unregulated supplements can contain hidden drugs causing misleading symptoms and test results.
27 citations
,
October 1945 in “Endocrinology” Synthetic hormone treatment reduces melanin and hair growth in rats.
January 2022 in “Current Enzyme Inhibition” New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.
5 citations
,
October 1990 in “Archives of Dermatology”
1 citations
,
July 2019 in “The journal of applied laboratory medicine” Venous catheterization may help diagnose the cause of female hyperandrogenism when imaging is unclear.
6 citations
,
July 2024 in “Heliyon” Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.
13 citations
,
February 2022 in “JAMA Dermatology” Spironolactone does not increase cancer risk and may lower prostate cancer risk, but more research is needed.
October 2007 in “Journal of Korean Medicine Rehabilitation”
1 citations
,
November 2007 in “Humana Press eBooks” Most cases of high male hormone levels in women are due to polycystic ovary syndrome.
46 citations
,
June 1983 in “Cleveland Clinic Journal of Medicine” Higher DHEAS levels may cause hair loss in women by disrupting hair growth.
4 citations
,
October 1988 in “Clinics in Dermatology” Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.
October 2024 in “Journal of the Endocrine Society” Leydig cell tumors can cause high testosterone and symptoms like hair loss in postmenopausal women, but surgery can improve these symptoms.
October 2004 in “DOAJ (DOAJ: Directory of Open Access Journals)” Men with hair loss don't necessarily have higher levels of the hormone DHEA-S, but this hormone tends to decrease with age.