research 237 Unveiling Skin Cancers Pathophysiology via the Modeling of Xeroderma Pigmentosum Disease Modeling Using CRISPR-Cas9 Technology
Blocking the JAK/STAT pathway may help reduce skin sensitivity in Xeroderma pigmentosum.
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research Original papers A study on efficacy of 308 nm excimer light therapy in alopecia areata
308 nm excimer light therapy may help hair regrowth in alopecia areata with delayed results and no serious side effects.
research The use of phototherapy with different wavelengths in the treatment of Androgenetic Alopecia
Phototherapy with red and blue light can effectively treat hair loss.
research Low-level light-assisted photodynamic therapy using a wearable cap-like device for the treatment of actinic keratosis of the scalp
A wearable cap-like device using light therapy reduced scalp skin lesions by 71% and was painless.
research The Photoprotective Effect of S-Methylmethionine Sulfonium in Skin
S-Methylmethionine sulfonium can protect skin from UVB damage.
research Skin cancer and sun protection practices in Fanconi anemia patients: A cross-sectional study
research 509 Using the human iPSCs-derived sensory neurons re-innervated skin ex vivo model to investigate mast cell-nerve fiber cross-talk in solar elastosis
Nerve fibers may worsen mast cell activity, leading to abnormal elastic fiber buildup from sun exposure.
research Mitigation of epidermal growth factor receptor inhibitor-induced side effects utilizing melanin and vascular-specific lasers: A case report series
Lasers can help reduce skin side effects from cancer treatment.
research Actinic Hyperkeratosis Treated with Retinol Combined with A Polylysine Biovector: A Case Report
Encapsulated retinol may effectively treat actinic keratosis without side effects.
research Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation induced tissue damage
UV exposure harms skin by causing fibroblast loss, but T cells help fibroblast survival.
research A Definitive Role of Ornithine Decarboxylase in Photocarcinogenesis
Inhibiting ODC can prevent UV-induced skin cancer.
research 686 UVB irradiation with anti-CD154 antibody prolonged the survival of hair follicle allografts in humanized mice
Combining UVB irradiation and anti-CD154 antibody improves hair follicle transplant survival.
research A case report of verruca vulgaris on basis of alopecia areata successfully treated with diphenylcyclopropenone
Diphenylcyclopropenone (DPCP) effectively treated both alopecia areata and verruca vulgaris.
research 644 Response of distinct human dermal fibroblast lineages to visible radiation: Potential for differential light-based therapy
Different types of human skin cells respond uniquely to various colors and doses of light, which could lead to specialized light treatments for skin conditions.
research The Therapeutic and Preventive Effects of Light‐Emitting Diode (LED ) for Post‐Inflammatory Erythema and Hyperpigmentation: A Pilot Study
830 nm LED light effectively treats and prevents skin redness and dark spots, while 590 nm LED light only helps prevent them.
research Efficacy and Influence Factors of 308‐nm Excimer Lamp with Minoxidil in the Treatment of Alopecia Areata
Using a 308-nm excimer lamp with minoxidil promotes hair growth in Alopecia Areata patients, especially younger ones or those with smaller bald spots.
research Clinical Snippets
Early sunburn treatment with certain inhibitors may reduce skin cancer risk.
research Protein Kinase C Epsilon Signals Ultraviolet Light-induced Cutaneous Damage and Development of Squamous Cell Carcinoma Possibly Through Induction of Specific Cytokines in a Paracrine Mechanism¶
Protein kinase C epsilon may increase skin cancer risk by affecting nearby cells.
research Weathering of the hairless scalp: a study using skin capacitance imaging and ultraviolet light-enhanced visualization
The study found that long-term sun exposure does not significantly affect follicular plugs on the scalp, and the scalp's appearance is unique compared to other body parts.
research Dermoscopy and Ultraviolet-Enhanced Fluorescence Dermoscopy (UEFD) Increase the Accuracy of Diagnosis and Are Useful in Assessing the Effectiveness of Kerion celsi Treatment
Advanced dermoscopy techniques improve diagnosis and treatment monitoring for Kerion celsi but don't guarantee full hair regrowth.
research M2 Macrophage and Extracellular Matrix Genes Are Enriched in High‐Activity Lichen Planopilaris
Higher activity in lichen planopilaris is linked to certain immune and tissue genes.
research 880 Triptolide (TRP), a diterpenoid, shows a strong efficacy and a safe profile in the topical treatment of actinic keratosis lesions in a UV-B-induced mouse model
Triptolide effectively and safely reduces actinic keratosis lesions in mice.
research ALOE VERA IN THE TREATMENT OF ROENTGEN ULCERS AND TELANGIECTASIS
Aloe vera healed severe skin damage and restored normal skin in five weeks.
research Efficacy and safety of anthralin in combination with diphenylcyclopropenone in the treatment of alopecia areata: a retrospective case series
Combining DPCP and anthralin helps regrow hair in some alopecia areata patients.
research Systemic Treatments for Lichen Planopilaris and Frontal Fibrosing Alopecia: A Retrospective Study of 315 Patients
Methotrexate is best for lichen planopilaris, and retinoids are best for frontal fibrosing alopecia, but side effects are common.
research Erosive Pustular Dermatosis: A Manifestation of Immunosenescence A Report of 8 Cases
Erosive pustular dermatosis in elderly people may be linked to aging immune systems and skin damage.
research The secondary role of UV light in swimmers melanoma genesis
Hydrogen peroxide is a major risk factor for melanoma in swimmers, more than UV light.
research Role of UVA-driven cellular senescence via mTOR activation in dihydrotestosterone-induced hair loss in androgenetic alopecia mouse model
UVA exposure worsens hair loss by activating a specific cell pathway.
research Assessing the Efficacy of Monthly 308 nm Excimer Lamp Double-Stacked Pulse Adjusted Therapy for Alopecia Areata
308 nm excimer lamp therapy is effective for alopecia areata but less so for severe cases.
research Topical ALA-Photodynamic Therapy for Acne Can Induce Apoptosis of Sebocytes and Down-regulate Their TLR-2 and TLR-4 Expression
ALA-photodynamic therapy helps reduce acne by causing acne cell death and lowering certain skin protein levels.