Certain medications, especially 5-alpha reductase inhibitors, are commonly linked to erectile dysfunction.
17 citations
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April 2006 in “Brain Research” 5α-reduced neurosteroids may help regulate glial cell differentiation.
25 citations
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July 2006 in “Journal of Neurochemistry” Progesterone affects GABAA receptor function by altering δ subunit levels.
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October 2011 in “Psychoneuroendocrinology” Finasteride may help improve certain brain function issues linked to dopamine.
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January 2004 in “Journal of Neuroscience” Neurosteroids regulate synaptic inhibition in the spinal cord and may help manage spinal pain.
164 citations
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January 2003 in “Drugs” 39 citations
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January 2010 in “Trends in Parasitology” Anticancer drugs like methotrexate and trimetrexate could be effective and safe for treating malaria at low doses.
Monocyclic aromatic compounds are important for developing various drugs and treatments.
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September 1972 in “British Journal of Pharmacology” PCPA induces hypersexual behavior in male rats regardless of age or castration status.
28 citations
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September 2000 in “Journal of Medicinal Chemistry” Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.
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January 1978 in “PubMed” Certain chemical changes to cortisol and progesterone can increase or decrease their ability to inhibit hair growth.
14 citations
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September 2017 in “Hormones and behavior” δ-GABAA receptors affect alcohol consumption based on the estrous cycle and influence movement regardless of the cycle.
33 citations
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December 2017 in “Journal of neuroendocrinology” Sex and stress steroids quickly change brain cell structures in the hippocampus.
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February 2016 in “Irish journal of psychological medicine” Mirtazapine may cause hair loss and change hair color, but stopping the drug can reverse these effects.
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January 2019 in “Elsevier eBooks” Neuroactive steroids may affect the risk and treatment of alcohol use disorders.
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July 2023 in “Neuroscience & Biobehavioral Reviews” Endogenous neurosteroids may set a baseline mood.
5alpha-DHP may be a safe, effective treatment for certain seizures without causing sedation.
26 citations
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August 2004 in “Alcoholism Clinical and Experimental Research” Ethanol-induced motor incoordination in rats is not affected by increased neuroactive steroids.
May 2024 in “Brain disorders” Agmatine may help reduce seizures linked to hormone changes in female rats.
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June 2007 in “Pharmacology Biochemistry and Behavior” Blocking progesterone metabolism can cause depression-like behavior in mice.
April 2020 in “Online journal of complementary & alternative medicine” Some medications can help increase sexual desire and function in women.
28 citations
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January 1996 in “Skin Pharmacology and Physiology” Minoxidil boosts hair cell growth, while cyclosporin does not.
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June 2008 in “British Journal of Clinical Pharmacology” Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
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January 2007 in “Side effects of drugs annual” Dermatological treatments can have significant side effects, including allergic reactions, sexual dysfunction, and increased cancer risk.
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July 2011 in “Journal of Neuroscience” Ethanol boosts brain steroid production by activating NMDA receptors, affecting memory formation.
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September 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Adding zinc to pyrithione zinc improves its effectiveness against scalp conditions like dandruff.
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December 2022 in “Toxins” Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.
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November 2018 in “Psychoneuroendocrinology” Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.
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January 1970 in “Journal of Bangladesh College of Physicians and Surgeons” Early diagnosis and genetic counseling are crucial for managing adrenoleukodystrophy.
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October 2017 in “Journal of Mind and Medical Sciences” Finasteride treatment should be personalized to individual mental profiles.