Careful diagnosis is crucial for premature pubarche, as 20% of cases have other conditions.
January 2017 in “Journal of Investigative Dermatology Symposium Proceedings” The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
119 citations
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June 2021 in “Heliyon” Licorice has many health benefits but should be used carefully due to possible side effects.
68 citations
,
August 2009 in “American Journal of Medical Genetics Part A” A new classification for trichothiodystrophy helps identify genetic causes and potential treatments.
27 citations
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September 2017 Pubic hair transplantation can improve self-esteem in those with sparse pubic hair.
26 citations
,
July 2020 in “Fertility and Sterility” Male infertility and genitourinary birth defects are often linked to genetic issues.
20 citations
,
September 2015 in “Pediatric Annals” PCOS in teen girls should be managed with lifestyle changes and sometimes medication to improve symptoms and health.
14 citations
,
December 2009 in “Der Hautarzt”
6 citations
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August 2023 in “European journal of endocrinology” The 2023 guideline advises a detailed approach for PCOS, focusing on early detection, lifestyle and medical treatments, and managing health risks.
5 citations
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June 2018 in “Journal of Diabetes, Metabolic Disorders & Control” Women with PCOS may have higher bad cholesterol and are at risk for blood sugar issues; lifestyle changes are recommended.
4 citations
,
September 2025 in “Biomolecules” The effect of GLP-1 RAs on erectile function is unclear and needs more research.
3 citations
,
September 2025 in “Frontiers in Cardiovascular Medicine” Women with PCOS have a higher risk of heart disease.
2 citations
,
December 2019 in “Cureus” A patient with a scalp condition and benign skin tumor experienced hair loss and did not improve with treatment, choosing not to have surgery despite a small cancer risk.
1 citations
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December 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Keeping β-catenin levels high in mammary cells disrupts their development and branching.
1 citations
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February 2016 in “Cell Transplantation” Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.
November 2025 in “Clinical and Translational Allergy” The consensus provides guidelines for safely stopping danazol in hereditary angioedema treatment.
February 2024 in “Medicina-lithuania” Obesity and bariatric surgery can cause hair thinning and temporary hair loss due to nutritional deficiencies and stress.
January 2024 in “Skin appendage disorders” Environmental pollutants can damage hair health and cause hair loss.
Thermal spring waters and their microbes could be good for skin health and treating some skin conditions in skincare products.
June 2020 in “Medicina estética (Madrid)” Female pattern hair loss is common and should be treated early to prevent worsening, with Minoxidil being the main approved treatment.
June 2020 in “Medicina estética” More research is needed to find effective treatments for Female Pattern Hair Loss.
40 citations
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July 2016 in “Pediatrics in review” Puberty involves complex hormonal changes, varies by gender and ethnicity, and requires careful monitoring for abnormalities.
29 citations
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February 2016 in “Scandinavian journal of urology” Late puberty may slightly lower prostate cancer risk, baldness is not linked to overall risk but less so with aggressive types, ibuprofen use may increase risk, and vitamins show no effect on risk.
October 2013 in “International Journal of Pediatric Endocrinology/International journal of pediatric endocrinology” A boy with early puberty and laughing seizures was treated, stopping seizures and slowing puberty.
29 citations
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July 2011 in “Pediatrics in review” Accurate assessment of puberty using Tanner staging is crucial for identifying normal and abnormal development.
September 2002 in “Fertility and sterility” Girls with PCOS often start puberty earlier and have signs of insulin resistance from a young age.
2 citations
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April 2021 in “PLoS ONE” Rural Bangladeshi girls mature later than peers in other low and middle-income countries due to poor nutrition and socioeconomic conditions.
192 citations
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January 1976 in “The Journal of Clinical Endocrinology & Metabolism” Androgen levels increase with puberty and are linked to sexual hair development.
January 2026 in “Reproductive Toxicology” High coffee intake during pregnancy may cause earlier puberty in daughters.
30 citations
,
March 1980 in “European Journal of Endocrinology” Adrenal androgens are important for puberty and are influenced by genetics.