Efficacy and Mechanism of Topical Shen Bai Hair Growing Decoction Against Androgenetic Alopecia

    February 2024 in “ ACS Omega ”
    Mingxi Li, Xiujun Zhang, Yan Wang, Xiang Bai, Zhaoyi Liu, Wenwen Zhang, Xiaohong Liu, Ruoxi Guo
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    TLDR The Shen Bai Hair Growing Decoction may help treat hair loss by promoting hair growth and reducing inflammation.
    The research involved 50 male C57BL/6J mice to study the effects of Topical Shen Bai Hair Growing Decoction (TSBHGD), a Traditional Chinese Medicine, on Androgenetic Alopecia (AGA). The study found that TSBHGD promoted hair growth, improved skin color, increased hair follicle counts in the anagen phase, and decreased counts in the telogen phase. It also reduced inflammatory markers TNF-α and IL-6. The main chemical components of TSBHGD were identified as 13 organic acids, 8 flavonoids, 6 quinones, 5 coumarins, and 3 triterpenoid saponins. The study concluded that TSBHGD could potentially treat AGA, supporting the clinical use of Traditional Chinese Medicine in alopecia treatment.
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