February 2017 in “The Journal of Sexual Medicine” Long-term testosterone treatment helps men with low testosterone levels lose weight.
408 citations
,
May 2004 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.
September 2014 in “PubMed Central” BPH treatments can cause sexual side effects affecting quality of life.
13 citations
,
December 2017 in “CNS Neuroscience & Therapeutics” Finasteride affects young male rats' brain function and behavior negatively.
35 citations
,
January 2012 in “The Journal of Sexual Medicine” Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.
Blocking 5α-reductase can reduce sleep deprivation-related behavioral issues in rats.
11 citations
,
January 2016 in “The Journal of Sexual Medicine” Young women with nonclassic congenital adrenal hyperplasia may experience worse sexual function and mild depression compared to healthy women.
1 citations
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January 2002 in “Yaoxue jinzhan” Finasteride reduces sperm count and affects male reproductive function, while Epristeride does not.
January 1983 in “Elsevier eBooks” Masculinization in affected individuals occurs gradually after puberty due to hormone changes.
November 2025 in “Вопросы современной педиатрии” Treating Netherton syndrome with growth hormone and dupilumab improves growth safely.
November 2024 in “Scientific Reports” Chemotherapy for male germ cell tumors often leads to hypogonadism and related symptoms.
7 citations
,
May 2017 in “Behavioural brain research” Changing neuroactive steroid levels early in life can affect how adult rats respond to alcohol's stimulating effects.
17 citations
,
January 1984 in “Psychotherapy and psychosomatics” Antiandrogen treatment can reduce sexual enjoyment in women with excess male hormones, especially those in stable relationships.
1 citations
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April 2022 in “AACE clinical case reports” A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.
Individualized treatment plans, including lifestyle changes and specific medications, are crucial for managing PCOS in adolescents.
11 citations
,
February 2003 in “Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology” Acne and increased body hair in teenage girls are normal but severe cases may need hormone evaluation and treatment can prevent diabetes linked to PCO.
The oral testosterone effectively increased testosterone levels and reduced SHBG, showing promise for treating testosterone deficiency.
26 citations
,
September 2005 in “Pharmacology Biochemistry and Behavior” 5alpha-reductase 2 is crucial for proper male brain development and sexual differentiation.
2 citations
,
December 2022 in “Journal of Clinical Medicine” Medications for glucose metabolism and weight control, combined therapy options, and herbal medicines may help regulate menstrual cycle in adolescents with PCOS.
17 citations
,
September 2013 in “The International Journal of Neuropsychopharmacology” 4 citations
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February 2009 in “Obstetrical & Gynecological Survey” Testosterone patches can modestly improve sexual function in postmenopausal women not on estrogen therapy.
241 citations
,
March 2000 in “The Journal of Urology” Men over 50 may experience hormone decline causing various symptoms, and proper management is crucial.
April 2019 in “Journal of the Endocrine Society” Middle-aged men with unusual hot flashes should be checked for pituitary tumors.
October 2010 in “Journal of Men's Health” Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.
August 2025 in “Journal of Pediatric Endocrinology and Metabolism” A rare ovarian tumor in a 2-year-old girl was successfully removed, normalizing her hormone levels.
March 2009 in “The Journal of Urology” Finasteride helps treat hair loss and prostate issues by blocking a hormone.
11 citations
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January 2000 in “Der Hautarzt” Male hypogonadism affects skin and hair, causing thin skin, less hair, and skin reactions to treatment.
May 2008 in “Trends in Urology Gynaecology & Sexual Health” Loop diuretics may double bone loss in elderly men, finasteride lowers prostate cancer risk but may increase high-grade tumors, abarelix reduces testosterone quickly, and transdermal testosterone offers minimal sexual benefit for women.
2 citations
,
December 1994 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.
64 citations
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March 1984 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.