September 2023 in “The Journal of clinical endocrinology and metabolism” Genetic risk for PCOS can affect children's growth, metabolism, and development from early life into adulthood.
218 citations
,
December 2011 in “Advances in Urology” The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
155 citations
,
December 2003 in “British Journal of Dermatology” Hair loss increases with age; alcohol raises risk, more female partners lowers it.
116 citations
,
December 2013 in “The Journal of Pediatrics” Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.
103 citations
,
June 2007 in “Endocrinology and Metabolism Clinics of North America” Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.
78 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.
63 citations
,
March 2011 in “Clinical Endocrinology” Evaluate postmenopausal women with high androgen levels using medical history, physical exams, lab tests, and imaging to manage health risks.
61 citations
,
October 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” The document concludes that accurate diagnosis is crucial for effectively treating common scalp disorders, which often have similar symptoms.
59 citations
,
December 2016 in “Clinical, Cosmetic and Investigational Dermatology” Acne keloidalis nuchae is a tough-to-treat condition that greatly affects quality of life, especially in men of African descent.
41 citations
,
October 2011 in “Journal of Dermatology” Finasteride 1 mg effectively and safely increases hair growth in Japanese men with hair loss.
40 citations
,
July 2008 in “Drug Discovery Today” Current treatments for male pattern baldness include minoxidil and finasteride, with new options being developed.
36 citations
,
September 2014 in “Paediatric drugs” More pediatric-specific research and guidelines are needed to improve hidradenitis suppurativa treatment in children and adolescents.
35 citations
,
May 1986 in “Clinics in endocrinology and metabolism” The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.
32 citations
,
May 2018 in “Cell Cycle” Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.
29 citations
,
April 2013 in “Mycoses” A young man was initially misdiagnosed with a scalp condition but was found to have a fungal infection, which improved with antifungal treatment.
26 citations
,
October 2016 in “Clinics in Dermatology” Hormonal treatments can improve acne, but they come with potential side effects and risks.
23 citations
,
May 1984 in “Journal of the American Geriatrics Society” Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.
20 citations
,
January 2014 in “Journal of the European Academy of Dermatology and Venereology” The critique highlights an error in a review about hair loss treatment, stressing the need for accurate information and caution due to poor evidence quality.
20 citations
,
August 2005 in “Journal of Cutaneous Pathology” The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.
15 citations
,
December 2016 in “Revista Da Associacao Medica Brasileira” Polycystic ovary syndrome is a common hormonal disorder in women, linked to increased risk of metabolic and heart diseases, and needs more research for better understanding and treatment.
11 citations
,
April 2015 in “International Journal of Cosmetic Science” Adenosine helps grow thicker hair in Japanese men with hair loss.
10 citations
,
December 2005 in “Aktuelle Dermatologie” Alfatradiol (0.025%) is an effective and safe treatment for hair loss in both women and men.
8 citations
,
January 1991 in “European Urology” Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.
7 citations
,
January 2015 in “Case reports in genetics” Using SNP array testing helped quickly find the gene causing Woodhouse-Sakati syndrome in two related individuals.
6 citations
,
October 2020 in “Endocrine journal” A patient with Werner syndrome showed a range of aging-like symptoms and metabolic issues, underscoring the need for early detection and treatment.
6 citations
,
April 2019 in “Journal of Pediatric Endocrinology and Metabolism” Metformin improved menstrual cycle regularity and signs of hyperandrogenism in adolescent girls with type 1 diabetes but did not improve blood sugar control.
4 citations
,
January 2020 in “Obstetrics and Gynecology Reports” Obese women with PCOS have lower vitamin D levels.
3 citations
,
March 2022 in “Korean Journal of Family Medicine” Doctors should consider SLE in males even if antinuclear antibody tests are negative.
3 citations
,
January 2017 in “International journal of research - granthaalayah” The traditional hair pack effectively reduced dandruff without any side effects.
3 citations
,
January 2008 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Early diagnosis and treatment of Hidradenitis Suppurativa are important to prevent serious physical and mental effects.