research Hormonal prevention of prostate cancer
Suppressing certain hormones might help prevent prostate cancer.
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research Environmental exposure to platinum group elements released by automotive catalytic converters: the risk for children
Children are at risk of health issues from exposure to platinum group elements from car exhausts.
research Characterizing Disease Features and Other Medical Diagnoses in Patients With Pityriasis Rubra Pilaris
PRP patients show varied symptoms and need more research to understand related conditions.
research The Role of 5αR Inhibitors in the Early Growth of Pca Cells
5αR inhibitors help slow early prostate cancer cell growth, suggesting combined treatments are needed.
research PD23-01 INHIBITOR OF 5A-REDUCTASE TYPES II PROMOTES THE INFILTRATION OF CD8+T CELLS IN BPH TISSUES.
Finasteride increases CD8+ T cells in BPH tissues.
research Crystallization Engineering in Aza-Steroid: Application in the Development of Finasteride
A new method was developed to purify finasteride for better medical use.
research Putting it all together: How do primary care physicians interpret and use the results of prevention trials?
Primary care doctors rarely use cancer prevention drugs due to concerns about side effects, costs, and effectiveness.
research 5α-Reductase: History and Clinical Importance
5α-reductase inhibitors like finasteride and dutasteride effectively treat BPH by reducing DHT levels.
research 5α- Reductase Inhibitors in Prostate Cancer: An Overview
5α-reductase inhibitors like Finasteride and Dutasteride may help manage prostate cancer by blocking testosterone conversion.
research Attenuation of 5α-reductase-mediated progesterone metabolism promotes differentiation of human endometrial stromal cells for the establishment of pregnancy
Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.
research PA30 Evaluation of markers of inflammation and oxidative stress in patients with premature canities
Premature canities is linked to low vitamin D and B12, family history, and higher MHR.
research Submission to the College of Physicians and Surgeons of Ontario Re: Medical Assistance in Dying
The document concludes that forcing doctors to assist in euthanasia against their will is dangerous and goes against democratic values.
research PROSPECTIVE EVALUATION ON SEXUAL DYSFUNCTION PERSISTENCE, WORSENING OR IMPROVEMENT IN BPH PATIENTS AFTER FINASTERIDE OR DUTASTERIDE TREATMENT
Finasteride and dutasteride can affect sexual function in BPH patients.
research Submission to the College of Physicians and Surgeons of Ontario Re: Professional Obligations and Human Rights
The submission argued that CPSO's referral policy undermines doctors' civil liberties and recommended changes to protect conscientious objections.
research Inhibitory Effects of Pueraria mirifica Aqueous Extracts on 5α-reductase and Prostate Histomorphometry in Testosterone-induced Benign Prostatic Hyperplasia Sprague Dawley Rats
Pueraria mirifica extract may help treat benign prostatic hyperplasia.
research Atypical Juvenile Pityriasis Rubra Pilaris: A Case Report of Early Onset With Late Diagnosis
A rare skin condition in a 17-year-old was diagnosed late, stressing the need for careful evaluation and genetic testing.
research PCPT Results Could Affect Trial on Testosterone Replacement
The trial on testosterone replacement therapy in older men faced concerns due to prostate cancer risk.
research 5-α-Reductase inhibitors for prostate cancer chemoprevention: an updated Cochrane systematic review
5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.
research Adherence with protocol medication use and mortality from unrelated causes in a prevention trial
Not taking prescribed medications properly can lead to higher death rates from unrelated health conditions.
research Uromedic® Pumpkin Seed Derived Δ7-Sterols, Extract and Oil Inhibit 5α-Reductases and Bind to Androgen Receptor <em>in Vitro</em>
Pumpkin seed products may help improve prostate and bladder health by blocking certain enzymes and hormone receptors.
research Influence of knowledge and beliefs on consumption of performance enhancing agents in north-western Saudi Arabia
More knowledge about the risks of performance-enhancing agents leads to less use in north-western Saudi Arabia.
research A systematic study of determination and validation of finasteride impurities using liquid chromatography
Method found to accurately identify finasteride impurities using liquid chromatography.
research Case for diagnosis. Pregnant woman in the 3rd trimester with pruritic papules and pustules on the trunk. Pruritic folliculitis of pregnancy
The woman has a rare, harmless skin condition specific to pregnancy that causes itchy bumps and will go away after she gives birth.
research Étude PCPT : les biais attendus et leur gestion
Systematic end-of-trial biopsies are the most reliable way to assess outcomes.
research PCPT, MTOPS and the use of 5ARIs: a Canadian consensus regarding implications for clinical practice
5ARIs like finasteride can help prevent prostate cancer and treat BPH, but guidelines should be updated to reflect this.
research Merck offers money back guarantee on finasteride
Merck will refund the cost of the drug finasteride if it doesn't improve symptoms within six months or if the patient needs surgery within two years.
research Purple corn extract improves benign prostatic hyperplasia by inhibiting 5 alpha-reductase type 2 and inflammation in testosterone propionate-induced rats
Purple corn extract may help reduce prostate enlargement and inflammation.
research Trapa bispinosa Roxb. Pericarp Extract Exerts 5α-Reductase Inhibitory Activity in Castrated Benign Prostatic Hyperplasia Model Mice
Trapa bispinosa Roxb. extract may help reduce prostate size and cell growth in BPH.
research 5-Alpha Reductase Inhibitors in Prostate Cancer: From Clinical Trials to Clinical Practice
5-Alpha reductase inhibitors may prevent prostate cancer but are not widely used due to concerns about trial relevance and potential risks, and more research is needed to confirm long-term benefits.
research The 19th Century Origins of Facial Cosmetic Surgery and John H. Woodbury
John H. Woodbury pioneered early U.S. cosmetic surgeries but ended in bankruptcy due to legal issues.