research Loss of Msx2 Function Down-Regulates the FoxE3 Expression and Results in Anterior Segment Dysgenesis Resembling Peters Anomaly
Loss of Msx2 function causes eye development issues similar to Peters anomaly.
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480-510 / 1000+ resultsresearch 0977 Pathogenic hallmarks of primary lymphocyte-mediated scarring alopecia revealed by single nuclear and spatial multiomics
Scarring alopecia involves increased immune cells and specific gene changes near damaged hair follicles.
research 1392 Activation of Id2 gene regulatory network ruling quiescence of hair follicle stem cells
Id2 gene helps keep hair follicle stem cells inactive.
research Replicative stress, stem cells and aging
Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.
research Investigating the roles of cellular senescence in embryogenesis and aging
Cellular senescence is crucial for normal embryonic development but contributes to aging in adults.
research Learning from nudity: lessons from the nude phenotype
The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.
research Mutation of the doublecortin gene in male patients with double cortex syndrome: Somatic mosaicism detected by hair root analysis
Hair root analysis can effectively detect somatic mosaicism in double cortex syndrome.
research 1381 Investigating the role of Mef2c in hair follicle cycling
MEF2C is crucial for normal hair cycle progression.
research Synchronously developing collet hairs in Arabidopsis thaliana provide an easily accessible system for studying nuclear movement and endoreduplication
Arabidopsis collet hairs are good for studying nuclear movement and DNA content increase during growth.
research Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming
Long-term skin biopsy cultures can produce many fibroblasts that remain functional and can be reprogrammed.
research 726 The Wnt-inhibitor Dkk4 is required for primary hair follicle induction and patterning
Dkk4 is necessary for the initial development and arrangement of hair follicles.
research Phospholipase C 1 is required for skin stem cell lineage commitment
Phospholipase Cδ1 is crucial for normal skin and hair development.
research LB1774 Establishing competent morphogenetic fields for tissue pattern regeneration in skin organoids
Skin organoids can regenerate hair by forming specific cell units with certain signals.
research Divergent molecular signatures of regeneration and fibrosis during wound repair
Disrupting YAP signaling in skin cells leads to scar-free healing directed by specific cell signals.
research Pulling force deforms hair follicle root sheath nuclei and surrounding dermal collagen matrix differently at infundibulum, isthmus and suprabulbar regions
Hair follicles respond differently to pulling forces in various regions.
research Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo
Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.
research 840 Early and late matrix progenitors form the terminally differentiated cell layers of the hair follicle
Early and late matrix progenitors in hair follicles create different cell layers, with early ones forming the companion layer and later ones forming the inner root sheath and hair shaft.
research Fibroblast Growth Factor 21 is Differentially Expressed in Flank Skin and Regulates the Proliferation of Hair Follicle Cells in Yak
research 743 Adipocyte stem cells are maintained by Pdgfα signaling in the skin
Pdgfα signaling helps maintain fat cells in the skin and is important for hair growth, wound healing, and fighting infections.
research Cell death in the skin
Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
research “Anisotrichosis”: A novel term to describe pattern alopecia
The document suggests "anisotrichosis" as a new term for hair thickness variation in common baldness.
research Molecular signaling in feather morphogenesis
Feather growth and regeneration involve complex patterns, stem cells, and evolutionary insights.
research Basal cell carcinomas acquire secondary mutations to overcome dormancy and progress from microscopic to macroscopic disease
Basal cell carcinomas need extra mutations to grow from small to large tumors.
research Exploring Mechanical Niches Identified by Hair Follicle Compression and How These Transduce Proliferation and Differentiation Cues in Epidermally Derived cells.
Less stiff collagen promotes higher cell growth in hair follicles.
research 0882 Patterning and regional specification of hairy skin
Secreted inhibitors of Wnt and IGF signaling control hair and tooth development, creating species-specific patterns.
research Organogenesis From Dissociated Cells: Generation of Mature Cycling Hair Follicles From Skin-Derived Cells
Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.
research Cyclin-dependent kinase inhibitors, p21waf1/cip1 and p27kip1, are expressed site- and hair cycle-dependently in rat hair follicles
p21waf1/cip1 and p27kip1 help in hair follicle differentiation in rats.
research Np63 Regulates Stem Cell Dynamics in the Mammalian Olfactory Epithelium
p63 is essential for activating and differentiating stem cells in the nose's olfactory tissue.
research Expression of nicastrin, NICD1, and Hes1 in NCSTN knockout mice: implications for hidradenitis suppurativa, Alzheimer’s, and liver cancer
research Phylloid terminal hair nevus: A unique clinical entity
A baby had a unique skin condition with a pale patch and surrounding dark hairs, not linked to other health issues.