research Drug Therapy in Polycystic Ovarian Syndrome
Low-dose flutamide-metformin therapy effectively improved PCOS symptoms in adolescent girls.
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360-390 / 1000+ results research Abstract- Poster
Lithium for bipolar disorder can cause skin problems like rashes, which go away when the medication is stopped.
research Progesterone promotes the survival of newborn neurons in the dentate gyrus of adult male mice
Progesterone helps adult male mice grow more neurons and improves memory.
research 554 Repurposing a clinical antimalarial for the therapeutic induction of lethal ER stress targeting BRAF-kinase inhibitor-resistant malignant melanoma
Mefloquine, an antimalarial drug, is effective in killing melanoma cells resistant to other treatments by causing lethal stress in the cells.
research Evidence- and consensus-based recommendations for the use of pegvaliase in adults with phenylketonuria
Pegvaliase is recommended for treating adults with phenylketonuria.
research Synthesis, antiproliferative, acute toxicity and assessment of antiandrogenic activities of some newly synthesized steroidal lactams
research Novel Quinazoline Derivative Induces Differentiation of Keratinocytes and Enhances Skin Barrier Functions against Th2 Cytokine-Mediated Signaling
SH-340 may improve skin barrier and help treat atopic dermatitis.
research Severe hair loss associated with psyc hotropic drugs in psychiatric inpatients—Data from an observational pharmacovigilance program in German-speaking countries
Some psychiatric drugs can cause severe hair loss, especially valproic acid, and it's more likely in women or those with thyroid issues or past hair loss.
research Desenvolvimento e caracterização de nanopartículas poliméricas carregadas com fosfato de clindamicina para tratamento tópico da acne vulgar
NP-AH-CDM-4 nanoparticles show promise for effective topical acne treatment.
research Physician Awareness of the Safe Use of Cyproterone Acetate in Europe: A Survey on the Effectiveness of Additional Risk Minimization Measures
Most European physicians know the risks and safe use of Cyproterone acetate, but few remember receiving official safety communications.
research Clinical efficacy and safety of low‐dose flutamide alone and combined with an oral contraceptive for the treatment of idiopathic hirsutism
Low-dose flutamide helps reduce excessive hair growth and is even more effective with birth control, without bad effects on blood fats.
research Therapeutic and skincare products used in hirsutism and hypertrichosis
Prescription tablets treat hirsutism, while over-the-counter foams treat hypertrichosis.
research Pegylated Liposomal Doxorubicin in the Treatment of Breast Cancer
PLD is an effective and safer alternative for treating breast cancer.
research Multi-Modal Imaging to Assess the Follicular Delivery of Zinc Pyrithione
Zinc pyrithione dissolves quickly on the skin and in hair follicles, especially in smaller particles.
research MON-407 The Double-Edged Sword of Methimazole: Managing Graves' Disease with a Twist
Methimazole can cause severe low platelet count in Graves' disease patients, so monitoring and alternative treatments are important.
research Alternative synthesis of the anti-baldness compound RU58841
A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.
research Doxil (Caelyx): an exploratory study with pharmacokinetics in patients with hormone-refractory prostate cancer
Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.
research The prolactin receptor as a therapeutic target in human diseases: browsing new potential indications
Blocking the prolactin receptor might help treat various diseases, but more research is needed.
research Allopregnanolone (AP) induces opioid inhibition of hypothalamo-pituitary-adrenal (HPA) axis responses to interleukin-1β (IL-1β) in pregnancy
Allopregnanolone and opioids together reduce stress hormone responses during pregnancy.
research Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors
The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.
research LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1.
LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
research Comprehensive Safety Exposure‐Response Analysis to Support Ritlecitinib Dose Selection
A 50 mg non-loading dose of ritlecitinib is safe for adults and adolescents.
research Die Behandlung androgenisierter Frauen mit intramuskulär applizierbarem Cyproteronacetat
Intramuscular cyproterone acetate effectively treats hirsutism and improves skin conditions in women with hyperandrogenism.
research Psychopharmacological Treatment of Trichotillomania in an Adolescent Case: Significant Improvement with Aripiprazole Augmentation
Adding aripiprazole to the treatment improved hair-pulling symptoms in a teenager.
research Core-shell and core-amphiphilic branched shell nanocarriers based on biodegradable hyperbranched polymers, as potential drug delivery systems
The new biodegradable nanocarriers safely and effectively deliver drugs into the skin.
research 5. Novel anticonvulsant effects of supraphysiological doses of progesterone in hippocampal-kindled mice
High doses of progesterone can reduce seizures in mice.
research Neural substrates of the emotional negativity bias as revealed by haemodynamic data
Cyproterone acetate is a safe treatment that causes mild feminizing effects in adolescent trans-girls.
research Topiramate vs Divalproex Sodium in the Preventive Treatment of Migraine: A Prospective “Real‐World” Study
Both topiramate and divalproex sodium effectively reduce migraine frequency and are generally well-tolerated.
research Trazodone and chlorpromazine a proposal treatment for syndrome post-finasteride and syndrome of post-selective serotonin reuptake inhibitors (post-SSRI)
Trazodone and chlorpromazine may help treat sexual dysfunction caused by finasteride and SSRIs.
research Design and Characterization of Baricitinib Incorporated PLA 3D Printed Pills by Fused Deposition Modeling: An Oral Pill for Treating Alopecia Areata
The study created 3D-printed pills that effectively release a hair loss treatment drug over 24 hours.