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The enzyme RDH12 plays a role in vision and retinal disease, with mutations leading to early onset visual loss and blindness, but the exact disease mechanism is unclear and there are no treatments yet.

PrPC is important for neural differentiation in cattle and mouse embryonic stem cells.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Cysteines in wool fibers are accessible and form important disulfide bonds.

Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.

Human cathepsin V can replace mouse cathepsin L to maintain normal skin and hair in mice.

TPA strongly increases ODC activity in certain skin cells, potentially aiding tumor growth.

Ornithine decarboxylase is crucial for hair growth regulation in mice.

A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

Twist1 is crucial for UVB-induced skin cancer development.

Carruthers' work advances understanding of skin biochemistry but needs clearer interpretation and more discussion on certain topics.

A substance called poly(I:C) increases a protein called carbonic anhydrase II in skin cells, which might help with skin defense and healing.

Truncated hHb1 keratin may play a role in breast cancer cell transformation.

Disrupted citric acid metabolism stops hair growth.

Hair plucking quickly increases antizyme, reducing a specific enzyme activity in rats.

A new type of pachyonychia congenita linked to a specific keratin gene mutation was found in two Pakistani families.

Human mitochondrial DNA polymerase makes very few errors, crucial for preventing degenerative diseases.

Researchers found two enzymes in Avicennia marina that help produce maslinic acid and corosolic acid, which have medicinal benefits.

A woman was diagnosed with porphyria cutanea tarda and improved with phlebotomy and lifestyle changes.

DGAT1 enzyme helps make diacylglycerols, waxes, and retinyl esters.

Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.

Researchers found a new gene variant linked to a rare bone disease, which doesn't always cause symptoms in carriers.

FTase and GGTase-I are essential for skin keratinocyte health.

The PP2A-B55α protein is essential for brain and skin development in embryos.

Physioxia improves keratinocyte protection against oxidative stress and better mimics real skin conditions.

We know less about human hair pigmentation than mouse coat color, but pH and cysteine levels are key factors.

The study found that thioglycolic acid breaks down hair bonds more consistently than l-cysteine, which is less damaging to hair.