![Synthesis, Biological Evaluation, and Molecular Docking of 4-Amino-2H-benzo[h]chromen-2-one Analogs Containing the Piperazine Moiety](/images/research/2ecf4eed-7dbe-4f1a-83db-739625546cdd/small/31808.jpg)
research Synthesis, biological evaluation and molecular docking of 4-Amino-2H-benzo[h]chromen-2-one (ABO) analogs containing the piperazine moiety
Analog 23 is a promising compound for prostate cancer treatment.
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570-600 / 1000+ results research Quantitative mapping of melanin in hair fibers using fluorescence lifetime imaging microscopy
research Supplementary figure S2
research Solubilities of Flutamide, Dutasteride, and Finasteride as Antiandrogenic Agents, in Supercritical Carbon Dioxide: Measurement and Correlation
Flutamide, dutasteride, and finasteride dissolve differently in supercritical carbon dioxide, with dutasteride dissolving the least.
research Structural characterization of polymorphs and molecular complexes of finasteride
Finasteride's molecular and crystal structures help develop new drug formulations.
research The Application of Radiochemical Techniques to the Study of the Interaction of Hair Fibers with Aqueous Solutions
Hair absorbs different substances from solutions based on pH levels.
research Modelling of the composition of emulsion medicines and cosmetics stabilized by a biocomplex of surfactant substances based on rhamnolipids Pseudomonas sp. PS-17
A semi-automated system can effectively help choose emulsion ingredients, simplifying the creation of medicinal and cosmetic products.
research In-Depth Exploration of Chemical Constituents from Justicia procumbens L. Through UHPLC-Q-Exactive Orbitrap Mass Spectrometry
132 compounds were found in Justicia procumbens L., including 77 new ones.
research A study on the conditioning effects of natural shampoos using the scanning electron microscope*
Natural shampoos made in the lab conditioned hair better than commercial ones with chemicals.
research THE APPLICATION OF PARTITION CHROMATOGRAPHY TO THE SEPARATION OF RARE EARTH ELEMENTS
PCOS causes hormonal imbalances and health issues like infertility and heart disease.
research Application of 2-Chloro-7-Nitrobenzo-2-Oxa-1, 3-Diazol (NBDCL) for Spectrophotometric Determination of Finasteride in Pharmaceutical Formulation
A new method using NBD-CL can accurately and precisely measure finasteride in medicine, and could be used regularly for quality control in the industry.
research METHOD DEVELOPMENT AND VALIDATION OF UV-SPECTROPHOTOMETRIC ESTIMATION OF FINASTERIDE IN BULK AND PHARMACEUTICAL DOSAGE FORM
A reliable, cost-effective method was developed for accurately measuring finasteride in medicines.
research Automated analysis of scanning electron microscopic images for assessment of hair surface damage
A new automated method accurately measures hair damage using microscopic images.
research Network-Based Drug Repositioning: Approaches, Resources, and Research Directions
The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.
research High-throughput and direct measurement of androgen levels using turbulent flow chromatography liquid chromatography-triple quadrupole mass spectrometry (TFC-LC-TQMS) to discover chemicals that modulate dihydrotestosterone production in human prostate cancer cells
Researchers found four natural compounds that can change DHT levels in prostate cancer cells.
research Evaluation of Therapeutic Potential of a Selective 5α-reductase Inhibitor against Glioblastoma: Molecular Docking and In Vitro Insights
![Synthesis of 5,6,6-[2H3]Finasteride and Quantitative Determination of Finasteride in Human Plasma at Picogram Level by an Isotope-Dilution Mass Spectrometric Method](/images/research/0026b639-99a8-455a-a986-c39aa65abfa9/small/2087.jpg)
research Synthesis of 5,6,6-[2H3]finasteride and quantitative determination of finasteride in human plasma at picogram level by an isotope-dilution mass spectrometric method
Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.
research Hair Oils
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research Dark cytotoxicity beyond photo-induced one of silica nanoparticles incorporated with RuII nitrosyl complexes and luminescent {Mo6I8} cluster units
research Spectrophotometric method for the estimation of finasteride in tablets
A new method accurately measures finasteride in tablets using color change and light absorption.
research Mechanotransduction in Androgenetic Alopecia: An In Silico Repositioning Study of PIEZO1 + MLCK Axis Using Cofolding and Pilosebaceous Single-Cell Atlas Constraints
Potential compounds may inhibit hair loss by targeting a non-androgen pathway.
research Validated LC-MS/MS Method for Simultaneous Quantification of Finasteride in Human Plasma
research Improved two‐dimensional electrophoretic mapping of Japanese human hair proteins; application to curved and straight Japanese human hairs; and protein identification by MALDI MS and MS/MS quadrupole time‐of‐flight mass spectrometry
The study found that minor protein differences between curved and straight Japanese hair are unlikely to significantly affect hair structure.
research DETERMINATION OF FINASTERIDE AND RELATED COMPOUNDS BY REVERSED-PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY. I. CHOOSING THE MOBILE PHASE COMPOSITION
Best results found using acetonitrile, water, and trifluoroacetic acid or methanol mixture.
research Second derivative spectrophotometric method for simultaneous determination of tamsulosin and finasteride in pharmaceutical formulations
A method was created in 2012 to accurately and precisely measure tamsulosin and finasteride in medicine using second derivative spectrophotometric method.
research DSC-investigations of alpha-keratins and the specific effects of chemical treatments on human hair
Chemical treatments weaken hair's thermal stability and structure.
research Reconnection of cysteine in reduced hair with alkylene dimaleates via thiol‐Michael click chemistry
A new method using 1,4-n-butylene dimaleate effectively repairs and strengthens damaged hair.
research Rosemary oil-based microemulsion co-delivering quercetin and adenosine promotes hair regeneration in androgenetic alopecia via multiple actions
research Molecular docking simulation studies on potent butyrylcholinesterase inhibitors obtained from microbial transformation of dihydrotestosterone
Metabolite 7 is a strong inhibitor for Alzheimer's disease management.
research Silver Oxide Based Nanoparticle Assisted Laser Desorption/Ionization Mass Spectrometry for the Detection of Low Molecular Weight Compounds
Silver oxide nanoparticles help detect small molecules effectively.