9 citations
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April 2019 in “International Journal of Molecular Sciences” Kojyl cinnamate ester derivatives can promote hair growth by increasing adiponectin production in fat tissues.
4 citations
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January 2018 in “Cosmetics” Spin traps like PBN could protect skin from pollution and sunlight in cosmetics but need more research for safe use.
3 citations
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May 2021 in “Molecules” Rosuvastatin improves lipid levels, reduces inflammation, but worsens insulin sensitivity in men with early-onset hair loss.
3 citations
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June 1995 in “International Journal of Gynecology & Obstetrics” Laser laparoscopy effectively reduces pelvic pain in women with mild to moderate endometriosis and is safe to use.
June 2008 in “British Journal of Dermatology” Herpes gestationis is linked to certain antigens, atopic eczema affects T cell populations and may be eased by breastfeeding, higher doses of anti-androgen treatment can improve androgenic alopecia, topical minoxidil increases hair thickness, long-term methotrexate therapy can cause liver fibrosis in psoriasis patients, and Lichen Sclerosus et Atrophicus patients aren't at higher risk for autoimmune disorders.
1744 citations
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August 2006 in “The Journal of Clinical Endocrinology and Metabolism” Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.
815 citations
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April 2010 in “The Journal of Clinical Endocrinology & Metabolism” Women with PCOS should be screened for heart disease risk and manage their health to prevent it.
773 citations
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August 2017 in “International Journal of Molecular Sciences” The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.
474 citations
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January 2012 in “Chemistry & biology” Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
414 citations
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August 2005 in “The Journal of Clinical Endocrinology and Metabolism” Polycystic ovary syndrome costs the U.S. over $4 billion a year, mainly from treating related health issues.
378 citations
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September 1998 in “The Journal of Clinical Endocrinology and Metabolism” PCOS affects about 4% of women in the southeastern U.S. equally across Black and White populations.
352 citations
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January 2006 in “The Journal of Clinical Endocrinology and Metabolism” Most women referred for excess male hormone symptoms had polycystic ovary syndrome (PCOS), with other conditions being less common.
185 citations
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August 2020 in “Mayo Clinic Proceedings” Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.
155 citations
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March 2006 in “The American Journal of Medicine” Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.
112 citations
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January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
92 citations
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June 2017 in “Journal of Plastic Reconstructive and Aesthetic Surgery” Microneedling is a safe and effective treatment for various skin conditions, often preferred for its fewer side effects and shorter recovery time.
54 citations
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October 2002 in “Journal of controlled release” Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.
51 citations
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November 2011 in “British Journal of Dermatology” A gene called HDAC9 might be a new factor in male-pattern baldness.
50 citations
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August 1985 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.
47 citations
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August 2000 in “Endocrine Reviews” The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.
46 citations
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September 2011 in “Journal of Endocrinology” Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
40 citations
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February 2005 in “Fertility and Sterility” Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.
39 citations
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April 2020 in “IntechOpen eBooks” Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
30 citations
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September 2003 in “Experimental Dermatology” Minoxidil helps prevent stress-caused hair loss in mice.
25 citations
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May 2020 in “Stem Cells Translational Medicine” ADSC-CE treatment safely increases hair density and thickness in androgenetic alopecia patients.
20 citations
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December 2000 in “Fertility and Sterility” The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.
16 citations
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October 2003 in “Journal of applied polymer science” 2-iminothiorane hydrochloride improves hair waving permanence without damage.
14 citations
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July 2011 in “Experimental Dermatology” Applying EGCG on the skin can prevent hair loss caused by testosterone in mice.
12 citations
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December 2019 in “International Journal of Molecular Medicine” Stem cells from umbilical cord blood may prevent hair loss caused by certain medications.