2 citations
,
May 2012 in “Annals of Oncology” Patients with advanced breast cancer and high hormone receptor levels who had surgery for ovarian/pelvic metastases lived longer, especially if they had high estrogen receptor levels.
53 citations
,
March 2003 in “Journal of Investigative Dermatology” Human skin cells have a high-affinity system for biotin transport, crucial for skin health.
231 citations
,
December 1999 in “Journal of Investigative Dermatology” Hair follicle size is mainly influenced by the number of cells and extracellular matrix volume, with cell number having a larger impact.
19 citations
,
October 2019 in “BMC Neuroscience” Blood hormone levels don't accurately show brain hormone levels in males.
101 citations
,
November 1992 in “Archives of Dermatology” Steroids help hair regrowth, and minoxidil slows post-steroid hair loss, but effects are temporary.
54 citations
,
May 1998 in “Urology” Men with enlarged prostates often have more severe baldness.
36 citations
,
January 2015 in “Dermatology” Bimatoprost was found to be safer and more effective than mometasone furoate for treating scalp hair loss.
9 citations
,
February 2022 in “Nature communications” Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.
1 citations
,
April 2015 in “Cytokine” Finasteride improves immune response and reduces organ damage after trauma hemorrhage in mice.
December 2021 in “Research Square (Research Square)” M-CSF-stimulated myeloid cells can cause alopecia areata in mice.
196 citations
,
September 2016 in “JCI insight” Ruxolitinib effectively regrows hair in most patients with severe hair loss.
193 citations
,
August 1985 in “Endocrinology” Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.
86 citations
,
March 1993 in “Toxicology and Applied Pharmacology” Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.
62 citations
,
June 2015 in “The Journal of Dermatology” People with alopecia areata have more Th17 cells and fewer Treg cells, which may be key to the condition's development.
45 citations
,
December 2014 in “Journal of the European Academy of Dermatology and Venereology” Plasmacytoid dendritic cells are a key factor in causing hair loss in alopecia areata and could help differentiate it from other hair loss conditions.
38 citations
,
November 2000 in “Hastings Center Report” The document suggests medicine should integrate biological and cultural factors and focus on holistic, equitable care.
36 citations
,
June 2014 in “International Journal of Dermatology” Dutasteride helps hair growth in those unresponsive to finasteride, but may cause more sexual dysfunction.
31 citations
,
June 2018 in “Dermatologic Surgery” Low-level light therapy safely improves hair coverage, thickness, and count in androgenetic alopecia patients.
29 citations
,
April 1995 in “Endocrinology” Finasteride doesn't affect bone density in male rats.
25 citations
,
June 2015 in “Scientific Reports” People with alopecia areata have a higher risk of stroke.
24 citations
,
May 2010 in “Veterinary dermatology” Oral ciclosporin A and topical treatments both reduce hair loss and scaling in dogs with sebaceous adenitis, but using both together is most effective.
22 citations
,
May 2011 in “American Journal of Clinical Dermatology” Recognizing and managing skin-related psychiatric disorders in children is crucial for effective treatment.
19 citations
,
September 2014 in “British Journal of Dermatology” Minoxidil foam 5% effectively treats hair loss in both frontal and vertex scalp regions.
18 citations
,
February 2001 in “Journal of International Medical Research” Hairgain® significantly increased hair growth and was well-tolerated by individuals with hair loss.
17 citations
,
March 2016 in “Liver international” Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.
16 citations
,
January 2019 in “Skin appendage disorders” Intralesional corticosteroids work best for mild alopecia areata, and DPCP works best for moderate to severe cases.
16 citations
,
December 2012 in “The Clinical Journal of Pain” Chronic scalp pain in trichodynia involves both body-wide and localized increased pain sensitivity.
15 citations
,
April 2020 in “Journal of Dermatological Treatment” Minoxidil and finasteride work best for hair loss; more research needed.
13 citations
,
June 2018 in “Journal of Womens Health” Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.
12 citations
,
January 2011 in “Photodermatology, photoimmunology & photomedicine” This therapy effectively treats resistant alopecia areata with minimal side effects.