37 citations
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January 1997 in “Journal of Pharmaceutical Sciences” Hairless rats absorb substances through their skin more easily than hairy rats.
25 citations
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July 1994 in “Journal of Cell Science” Immortalized rat dermal papilla cells can still induce hair growth.
21 citations
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December 2019 in “PloS one” The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.
11 citations
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August 1995 in “Journal of Investigative Dermatology” 4 citations
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July 1987 in “Laboratory Animals” Female rats aged 8 weeks are best for this model.
3 citations
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October 1979 in “Laboratory animals” Hairless rats are good for testing anti-inflammatory drugs, similar to haired rats, without needing to remove fur.
1 citations
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January 2012 in “Journal of Toxicologic Pathology” A rat had a cyst similar to a hair follicle structure.
September 2024 in “Advanced Biomedical Research” Chick embryo extract helps rat hair follicle stem cells become more like neurons.
Different rat and mouse strains respond differently to stress and alcohol, which may help us understand similar human mechanisms.
February 2014 in “PubMed” Modified rat hair follicle stem cells can help create artificial hair follicles, blood vessels, and skin.
98 citations
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April 1997 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride effectively blocks rat enzymes, but with varying methods and strength.
86 citations
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March 1993 in “Toxicology and Applied Pharmacology” Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.
83 citations
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November 2006 in “European Journal of Neuroscience” Progesterone protects rat brain cells by enhancing GABA A receptor activity.
72 citations
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September 1975 in “Biology of Reproduction” Most zinc in rat sperm is in the tail, linked to structures similar to hair keratin.
66 citations
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August 1990 in “Journal of Investigative Dermatology” Epithelial cell growth in rat hair follicles needs contact with mesenchymal cells through the extracellular matrix.
50 citations
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February 2004 in “Genomics” A gene mutation causes lanceolate hair in rats by disrupting hair shaft integrity.
48 citations
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December 2004 in “Differentiation” Tooth papilla cells can help regenerate hair follicles and grow hair.
45 citations
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January 2010 in “Journal of Veterinary Medical Science” A gene mutation causes curly hair and hair loss in rats.
37 citations
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January 2015 in “Evidence-based Complementary and Alternative Medicine” An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.
37 citations
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January 1975 in “Journal of Experimental Zoology” Epilation doesn't affect rat hair growth; thyroxine speeds it up, while estradiol slows it down.
35 citations
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October 2004 in “Biology of Reproduction” PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
26 citations
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April 2012 in “PubMed” Myofibroblasts in rat wound healing may come from blood vessel pericytes and perifollicular dermal sheath cells.
24 citations
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January 1989 in “Archives of biochemistry and biophysics” Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.
23 citations
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July 1979 in “Canadian journal of biochemistry” Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.
21 citations
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November 2014 in “Cytotechnology”
21 citations
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September 2008 in “Magnetic Resonance Imaging” MRI can effectively image skin structures noninvasively.
21 citations
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April 2008 in “Toxicologic Pathology” CI-1033 causes skin lesions in rats, similar to humans, due to EGF receptor inhibition.
20 citations
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November 1943 in “Experimental Biology and Medicine” Inositol helped prevent and cure hair loss in rats.
19 citations
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April 2015 in “European Journal of Pharmacology” Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.
18 citations
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October 2017 in “Drug Design Development and Therapy” DA-9401 helps protect rat testis from finasteride damage.