21 citations
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December 2019 in “PloS one” The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.
1 citations
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May 2023 in “International Journal of Applied Pharmaceutics” Placenta extract in novasomes improved rat hair growth better than minoxidil and placenta extract in liposomes.
59 citations
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September 2008 in “Experimental dermatology” Both mouse and rat models are effective for testing alopecia areata treatments.
38 citations
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June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
9 citations
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July 2007 in “PubMed” Atrazine causes birth defects in rats, and finasteride can reliably create a hypospadias model.
37 citations
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January 1997 in “Journal of Pharmaceutical Sciences” Hairless rats absorb substances through their skin more easily than hairy rats.
4 citations
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January 2006 in “PubMed” DHT deficiency may disrupt rat epididymis function by affecting estrogen receptors.
48 citations
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February 2016 in “Scientific Reports” Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.
4 citations
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July 1987 in “Laboratory Animals” Female rats aged 8 weeks are best for this model.
24 citations
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January 2007 in “The FASEB Journal” Neurosteroid withdrawal increases seizure frequency in a rat model of catamenial epilepsy.
18 citations
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March 2004 in “The Journal of Urology” Hypospadiac rats showed abnormal genital development, useful for studying human hypospadias.
1 citations
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May 2022 in “Research Square (Research Square)” Acetate helps reduce depression in rats with PCOS by lowering specific gene expression and DNA changes in the brain.
1 citations
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February 2019 in “Nanoscience and Nanotechnology Letters”
1 citations
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December 2017 in “JAMA Facial Plastic Surgery” Artificial hair implantation using scaffolds is possible and PHDPE is more biocompatible than ePTFE.
January 2014 in “Journal of Clinical and Investigative Dermatology” Young rats are better for testing hair loss treatments after chemotherapy.
Intramuscular injection of 131I is a safe and effective way to induce hypothyroidism in rats without harming muscle tissue.
October 2021 in “QJM: An International Journal of Medicine” The experiment successfully created a 3D model of a rat lung using a natural scaffold.
56 citations
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July 2014 in “PLoS ONE” Midazolam reduces PTSD-like behavior in rats by acting on specific brain receptors.
14 citations
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November 2005 in “Life sciences” Vitamin D3 may protect rat hair follicles from radiation damage.
53 citations
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November 2021 in “Molecular Human Reproduction” N-acetylcysteine may help treat uterine and placental issues in PCOS.
44 citations
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January 2012 in “Food and chemical toxicology” Ursolic acid can shrink the prostate and lower a hormone linked to prostate growth in rats.
43 citations
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June 2012 in “Lasers in Medical Science” Low-level laser treatment helped rats regrow hair faster after chemotherapy.
38 citations
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August 2003 in “International Journal of Urology” Finasteride and levofloxacin effectively reduce chronic bacterial prostatitis severity.
32 citations
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January 2022 in “Oxidative Medicine and Cellular Longevity” Cedrol may help treat rheumatoid arthritis due to its anti-inflammatory and antioxidant effects.
30 citations
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January 2015 in “BioMed Research International” Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.
25 citations
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February 2012 in “The Journal of Sexual Medicine” Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.
20 citations
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January 2017 in “Nutrition Research and Practice” Corn silk extract helps reduce prostate enlargement symptoms.
17 citations
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July 1995 in “International Journal of Dermatology” Minoxidil helps prevent hair loss from chemotherapy in rats.
15 citations
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January 2017 in “Experimental Neurology” Finasteride reduces movement issues in Parkinson's disease rats.
15 citations
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March 2014 in “Molecular Medicine Reports” α-spinasterol from Melandrium firmum can help reduce prostate enlargement.